Adaptive transcriptomic and immune infiltrate responses in the tumor immune microenvironment following neoadjuvant chemotherapy in high grade serous ovarian cancer reveal novel prognostic associations and activation of pro-tumorigenic pathways

The high rate of ovarian cancer recurrence and chemoresistance necessitates further research into how chemotherapy affects the tumor immune microenvironment (TIME). While studies have shown that immune infiltrate increases following neoadjuvant (NACT) chemotherapy, there lacks a comprehensive unders...

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Detalles Bibliográficos
Autores principales: James, Nicole E., Woodman, Morgan, De La Cruz, Payton, Eurich, Katrin, Ozsoy, Melih Arda, Schorl, Christoph, Hanley, Linda C., Ribeiro, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483165/
https://www.ncbi.nlm.nih.gov/pubmed/36131935
http://dx.doi.org/10.3389/fimmu.2022.965331

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