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Poly(2-alkyl-2-oxazoline)s: A polymer platform to sustain the release from tablets with a high drug loading

Sustaining the release of highly dosed APIs from a matrix tablet is challenging. To address this challenge, this study evaluated the performance of thermoplastic poly (2-alkyl-2-oxazoline)s (PAOx) as matrix excipient to produce sustained-release tablets via three processing routes: (a) hot-melt extr...

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Detalles Bibliográficos
Autores principales:	Samaro, Aseel, Vergaelen, Maarten, Purino, Martin, Tigrine, Ali, de la Rosa, Victor R., Goudarzi, Niloofar Moazami, Boone, Matthieu N., Vanhoorne, Valérie, Hoogenboom, Richard, Vervaet, Chris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483731/ https://www.ncbi.nlm.nih.gov/pubmed/36133793 http://dx.doi.org/10.1016/j.mtbio.2022.100414

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