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A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban
A 22-year-old woman was admitted to the hospital with complaints of headache and vomiting. Radiological examinations revealed cerebral sinus venous thromboses, pulmonary thromboembolism, and cavities in the left upper lung. Pulmonary tuberculosis was diagnosed based on sputum and gastric aspirate cu...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483779/ https://www.ncbi.nlm.nih.gov/pubmed/36133419 http://dx.doi.org/10.1016/j.rmcr.2022.101736 |
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author | Nishino, Koichi Akimoto, Takashi Mitsuoka, Hideyuki Terajima, Yutaka Arai, Yuta Masui, Yoshihiro Mimori, Tomoyasu Koike, Kengo Takahashi, Kazuhisa Sekiya, Mitsuaki |
author_facet | Nishino, Koichi Akimoto, Takashi Mitsuoka, Hideyuki Terajima, Yutaka Arai, Yuta Masui, Yoshihiro Mimori, Tomoyasu Koike, Kengo Takahashi, Kazuhisa Sekiya, Mitsuaki |
author_sort | Nishino, Koichi |
collection | PubMed |
description | A 22-year-old woman was admitted to the hospital with complaints of headache and vomiting. Radiological examinations revealed cerebral sinus venous thromboses, pulmonary thromboembolism, and cavities in the left upper lung. Pulmonary tuberculosis was diagnosed based on sputum and gastric aspirate culture. Heparin followed by warfarin was administered. Anti-tuberculosis agents including rifampicin were also initiated. Since the effect of warfarin did not reach the therapeutic level because of interaction with rifampicin, edoxaban was administered and thromboses were ameliorated. This report illustrates rare thrombotic complications in a TB-induced hypercoagulable state and the potential benefits and safety of edoxaban in combination with rifampicin. |
format | Online Article Text |
id | pubmed-9483779 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94837792022-09-20 A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban Nishino, Koichi Akimoto, Takashi Mitsuoka, Hideyuki Terajima, Yutaka Arai, Yuta Masui, Yoshihiro Mimori, Tomoyasu Koike, Kengo Takahashi, Kazuhisa Sekiya, Mitsuaki Respir Med Case Rep Case Report A 22-year-old woman was admitted to the hospital with complaints of headache and vomiting. Radiological examinations revealed cerebral sinus venous thromboses, pulmonary thromboembolism, and cavities in the left upper lung. Pulmonary tuberculosis was diagnosed based on sputum and gastric aspirate culture. Heparin followed by warfarin was administered. Anti-tuberculosis agents including rifampicin were also initiated. Since the effect of warfarin did not reach the therapeutic level because of interaction with rifampicin, edoxaban was administered and thromboses were ameliorated. This report illustrates rare thrombotic complications in a TB-induced hypercoagulable state and the potential benefits and safety of edoxaban in combination with rifampicin. Elsevier 2022-09-10 /pmc/articles/PMC9483779/ /pubmed/36133419 http://dx.doi.org/10.1016/j.rmcr.2022.101736 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Nishino, Koichi Akimoto, Takashi Mitsuoka, Hideyuki Terajima, Yutaka Arai, Yuta Masui, Yoshihiro Mimori, Tomoyasu Koike, Kengo Takahashi, Kazuhisa Sekiya, Mitsuaki A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban |
title | A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban |
title_full | A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban |
title_fullStr | A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban |
title_full_unstemmed | A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban |
title_short | A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban |
title_sort | case of tuberculosis-related cerebral venous sinus thrombosis and pulmonary thromboembolism successfully treated with edoxaban |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483779/ https://www.ncbi.nlm.nih.gov/pubmed/36133419 http://dx.doi.org/10.1016/j.rmcr.2022.101736 |
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