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A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban

A 22-year-old woman was admitted to the hospital with complaints of headache and vomiting. Radiological examinations revealed cerebral sinus venous thromboses, pulmonary thromboembolism, and cavities in the left upper lung. Pulmonary tuberculosis was diagnosed based on sputum and gastric aspirate cu...

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Autores principales: Nishino, Koichi, Akimoto, Takashi, Mitsuoka, Hideyuki, Terajima, Yutaka, Arai, Yuta, Masui, Yoshihiro, Mimori, Tomoyasu, Koike, Kengo, Takahashi, Kazuhisa, Sekiya, Mitsuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483779/
https://www.ncbi.nlm.nih.gov/pubmed/36133419
http://dx.doi.org/10.1016/j.rmcr.2022.101736
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author Nishino, Koichi
Akimoto, Takashi
Mitsuoka, Hideyuki
Terajima, Yutaka
Arai, Yuta
Masui, Yoshihiro
Mimori, Tomoyasu
Koike, Kengo
Takahashi, Kazuhisa
Sekiya, Mitsuaki
author_facet Nishino, Koichi
Akimoto, Takashi
Mitsuoka, Hideyuki
Terajima, Yutaka
Arai, Yuta
Masui, Yoshihiro
Mimori, Tomoyasu
Koike, Kengo
Takahashi, Kazuhisa
Sekiya, Mitsuaki
author_sort Nishino, Koichi
collection PubMed
description A 22-year-old woman was admitted to the hospital with complaints of headache and vomiting. Radiological examinations revealed cerebral sinus venous thromboses, pulmonary thromboembolism, and cavities in the left upper lung. Pulmonary tuberculosis was diagnosed based on sputum and gastric aspirate culture. Heparin followed by warfarin was administered. Anti-tuberculosis agents including rifampicin were also initiated. Since the effect of warfarin did not reach the therapeutic level because of interaction with rifampicin, edoxaban was administered and thromboses were ameliorated. This report illustrates rare thrombotic complications in a TB-induced hypercoagulable state and the potential benefits and safety of edoxaban in combination with rifampicin.
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spelling pubmed-94837792022-09-20 A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban Nishino, Koichi Akimoto, Takashi Mitsuoka, Hideyuki Terajima, Yutaka Arai, Yuta Masui, Yoshihiro Mimori, Tomoyasu Koike, Kengo Takahashi, Kazuhisa Sekiya, Mitsuaki Respir Med Case Rep Case Report A 22-year-old woman was admitted to the hospital with complaints of headache and vomiting. Radiological examinations revealed cerebral sinus venous thromboses, pulmonary thromboembolism, and cavities in the left upper lung. Pulmonary tuberculosis was diagnosed based on sputum and gastric aspirate culture. Heparin followed by warfarin was administered. Anti-tuberculosis agents including rifampicin were also initiated. Since the effect of warfarin did not reach the therapeutic level because of interaction with rifampicin, edoxaban was administered and thromboses were ameliorated. This report illustrates rare thrombotic complications in a TB-induced hypercoagulable state and the potential benefits and safety of edoxaban in combination with rifampicin. Elsevier 2022-09-10 /pmc/articles/PMC9483779/ /pubmed/36133419 http://dx.doi.org/10.1016/j.rmcr.2022.101736 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Nishino, Koichi
Akimoto, Takashi
Mitsuoka, Hideyuki
Terajima, Yutaka
Arai, Yuta
Masui, Yoshihiro
Mimori, Tomoyasu
Koike, Kengo
Takahashi, Kazuhisa
Sekiya, Mitsuaki
A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban
title A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban
title_full A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban
title_fullStr A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban
title_full_unstemmed A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban
title_short A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban
title_sort case of tuberculosis-related cerebral venous sinus thrombosis and pulmonary thromboembolism successfully treated with edoxaban
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483779/
https://www.ncbi.nlm.nih.gov/pubmed/36133419
http://dx.doi.org/10.1016/j.rmcr.2022.101736
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