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Higher serum sPD-L1 levels after radiotherapy indicate poor outcome in hepatocellular carcinoma patients

BACKGROUND: Our preclinical research reveals that radiotherapy (RT) promoted PD-L1 upregulation in tumor tissues and that higher PD-L1 after RT worsened the prognosis through immunosuppression. We sought to validate our experimental results in clinical cohorts and promote clinical application. PATIE...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Li, Zongjuan, Chen, Yixing, Yang, Ping, Hu, Yong, Zeng, Zhaochong, Du, Shisuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483785/
https://www.ncbi.nlm.nih.gov/pubmed/36115075
http://dx.doi.org/10.1016/j.tranon.2022.101537