Cargando…
Higher serum sPD-L1 levels after radiotherapy indicate poor outcome in hepatocellular carcinoma patients
BACKGROUND: Our preclinical research reveals that radiotherapy (RT) promoted PD-L1 upregulation in tumor tissues and that higher PD-L1 after RT worsened the prognosis through immunosuppression. We sought to validate our experimental results in clinical cohorts and promote clinical application. PATIE...
Autores principales: | Zhang, Yang, Li, Zongjuan, Chen, Yixing, Yang, Ping, Hu, Yong, Zeng, Zhaochong, Du, Shisuo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483785/ https://www.ncbi.nlm.nih.gov/pubmed/36115075 http://dx.doi.org/10.1016/j.tranon.2022.101537 |
Ejemplares similares
-
Gut microbiota modulate radiotherapy-associated antitumor immune responses against hepatocellular carcinoma Via STING signaling
por: Li, Zongjuan, et al.
Publicado: (2022) -
Outcomes of Image-Guided Moderately Hypofractionated Radiotherapy for Stage III Non-Small-Cell Lung Cancer
por: Zhang, Yang, et al.
Publicado: (2021) -
Induction Strategy for Locally Advanced Thymoma
por: Zhang, Yang, et al.
Publicado: (2021) -
Development and validation of a random forest model for predicting radiation pneumonitis in lung cancer patients receiving moderately hypofractionated radiotherapy: a retrospective cohort study
por: Zhang, Yang, et al.
Publicado: (2022) -
The correlation and prognostic value of serum levels of soluble programmed death protein 1 (sPD-1) and soluble programmed death-ligand 1 (sPD-L1) in patients with hepatocellular carcinoma
por: Chang, Boyang, et al.
Publicado: (2018)