Uterine malignant leiomyosarcoma associated with high levels of serum beta‐human chorionic gonadotropin: A case report

We present the case of a 54‐year‐old woman diagnosed with uterine leiomyosarcoma that produced beta‐human chorionic gonadotropin (β‐hCG), evident by both serum and immunohistologic examination. Based on this and similar cases from the available literature, β‐hCG‐producing sarcomas tend to have poore...

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Autores principales: Tsakos, Elias, Xydias, Emmanouil M., Ziogas, Apostolos C., Bimpa, Kanelina, Sioutas, Angelos, Zarampouka, Katerina, Tampakoudis, Georgios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483817/
https://www.ncbi.nlm.nih.gov/pubmed/36188042
http://dx.doi.org/10.1002/ccr3.6322
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author Tsakos, Elias
Xydias, Emmanouil M.
Ziogas, Apostolos C.
Bimpa, Kanelina
Sioutas, Angelos
Zarampouka, Katerina
Tampakoudis, Georgios
author_facet Tsakos, Elias
Xydias, Emmanouil M.
Ziogas, Apostolos C.
Bimpa, Kanelina
Sioutas, Angelos
Zarampouka, Katerina
Tampakoudis, Georgios
author_sort Tsakos, Elias
collection PubMed
description We present the case of a 54‐year‐old woman diagnosed with uterine leiomyosarcoma that produced beta‐human chorionic gonadotropin (β‐hCG), evident by both serum and immunohistologic examination. Based on this and similar cases from the available literature, β‐hCG‐producing sarcomas tend to have poorer prognosis, indicating that β‐hCG could potentially be used as a marker of disease status and response to the therapy; however, this association is inconsistent and should be further investigated.
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spelling pubmed-94838172022-09-29 Uterine malignant leiomyosarcoma associated with high levels of serum beta‐human chorionic gonadotropin: A case report Tsakos, Elias Xydias, Emmanouil M. Ziogas, Apostolos C. Bimpa, Kanelina Sioutas, Angelos Zarampouka, Katerina Tampakoudis, Georgios Clin Case Rep Case Report We present the case of a 54‐year‐old woman diagnosed with uterine leiomyosarcoma that produced beta‐human chorionic gonadotropin (β‐hCG), evident by both serum and immunohistologic examination. Based on this and similar cases from the available literature, β‐hCG‐producing sarcomas tend to have poorer prognosis, indicating that β‐hCG could potentially be used as a marker of disease status and response to the therapy; however, this association is inconsistent and should be further investigated. John Wiley and Sons Inc. 2022-09-19 /pmc/articles/PMC9483817/ /pubmed/36188042 http://dx.doi.org/10.1002/ccr3.6322 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Tsakos, Elias
Xydias, Emmanouil M.
Ziogas, Apostolos C.
Bimpa, Kanelina
Sioutas, Angelos
Zarampouka, Katerina
Tampakoudis, Georgios
Uterine malignant leiomyosarcoma associated with high levels of serum beta‐human chorionic gonadotropin: A case report
title Uterine malignant leiomyosarcoma associated with high levels of serum beta‐human chorionic gonadotropin: A case report
title_full Uterine malignant leiomyosarcoma associated with high levels of serum beta‐human chorionic gonadotropin: A case report
title_fullStr Uterine malignant leiomyosarcoma associated with high levels of serum beta‐human chorionic gonadotropin: A case report
title_full_unstemmed Uterine malignant leiomyosarcoma associated with high levels of serum beta‐human chorionic gonadotropin: A case report
title_short Uterine malignant leiomyosarcoma associated with high levels of serum beta‐human chorionic gonadotropin: A case report
title_sort uterine malignant leiomyosarcoma associated with high levels of serum beta‐human chorionic gonadotropin: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483817/
https://www.ncbi.nlm.nih.gov/pubmed/36188042
http://dx.doi.org/10.1002/ccr3.6322
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