Acute Immunoallergic Hepatitis in the Presence of Crohn’s Disease: A Case Presentation and Review of the Literature

In this case presentation, we discuss a patient with acute immunoallergic hepatitis after fluoroquinolone use. The patient presented with a complex perianal abscess two months after the initial procedure for a perianal abscess. He was placed on broad-spectrum antibiotics and underwent fecal diversion with partial colectomy to aid in wound care and diagnosis of Crohn’s disease. Acute hepatic insufficiency and ascites in the presence of a maculopapular rash suggested an immunoallergic reaction. The patient’s condition improved after discontinuation of the offending drug and utilizing intravenous steroids. The diagnosis of acute immunoallergic hepatitis was made based on clinical suspicion and a careful review of the patient’s medical records.