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Sestamibi scan in renal parathyroidectomy: a worthwhile preoperative exam?()

INTRODUCTION: Surgical treatment of hyperparathyroidism related to chronic kidney disease is a real challenge for Brazilian public health care. High cost medications and long waiting lines to perform preoperative exams, especially technetium Tc 99m Sestamibi (MIBI) are some of the reasons. Despite t...

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Autores principales: Neves, Murilo Catafesta das, Abrahão, Augusto Riedel, Abrahão, Marcio, Rosano, Marcello, Rocha, Lillian Andrade da, Machado, Hanna Karla Andrade Guapyassu, Santos, Rodrigo Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483931/
https://www.ncbi.nlm.nih.gov/pubmed/33303418
http://dx.doi.org/10.1016/j.bjorl.2020.10.009
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author Neves, Murilo Catafesta das
Abrahão, Augusto Riedel
Abrahão, Marcio
Rosano, Marcello
Rocha, Lillian Andrade da
Machado, Hanna Karla Andrade Guapyassu
Santos, Rodrigo Oliveira
author_facet Neves, Murilo Catafesta das
Abrahão, Augusto Riedel
Abrahão, Marcio
Rosano, Marcello
Rocha, Lillian Andrade da
Machado, Hanna Karla Andrade Guapyassu
Santos, Rodrigo Oliveira
author_sort Neves, Murilo Catafesta das
collection PubMed
description INTRODUCTION: Surgical treatment of hyperparathyroidism related to chronic kidney disease is a real challenge for Brazilian public health care. High cost medications and long waiting lines to perform preoperative exams, especially technetium Tc 99m Sestamibi (MIBI) are some of the reasons. Despite the reality that the aid of localization exams are questionable in this scenario, doctors are too apprehensive in performing surgery without it. OBJECTIVE: The study aimed at evaluating the efficacy of surgery for renal hyperparathyroidism without preoperative MIBI. METHODS: A total of 114 patients were surgically treated. Total parathyroidectomy with autotransplantation and subtotal parathyroidectomy were carried out without preoperative MIBI. RESULTS AND CONCLUSION: Among the 114 patients undergoing surgery, 37 had secondary hyperparathyroidism in dialysis replacement, and 77 patients had post-renal transplant persistent disease. We were successful in 107 cases with only 7 failures (93.8% of success rate). Among these failures, only one parathyroid gland was not found in 4 cases, 2 parathyroid glands were not found in 2 cases and in 1 patient the 4 glands were found but this patient remained hypercalcemic and a postoperative diagnosis of supernumerary parathyroid gland was made. Surgery for treatment of renal hyperparathyroidism proved to be an effective (93.8%) and reproductible procedure, even without MIBI.
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spelling pubmed-94839312022-09-20 Sestamibi scan in renal parathyroidectomy: a worthwhile preoperative exam?() Neves, Murilo Catafesta das Abrahão, Augusto Riedel Abrahão, Marcio Rosano, Marcello Rocha, Lillian Andrade da Machado, Hanna Karla Andrade Guapyassu Santos, Rodrigo Oliveira Braz J Otorhinolaryngol Original Article INTRODUCTION: Surgical treatment of hyperparathyroidism related to chronic kidney disease is a real challenge for Brazilian public health care. High cost medications and long waiting lines to perform preoperative exams, especially technetium Tc 99m Sestamibi (MIBI) are some of the reasons. Despite the reality that the aid of localization exams are questionable in this scenario, doctors are too apprehensive in performing surgery without it. OBJECTIVE: The study aimed at evaluating the efficacy of surgery for renal hyperparathyroidism without preoperative MIBI. METHODS: A total of 114 patients were surgically treated. Total parathyroidectomy with autotransplantation and subtotal parathyroidectomy were carried out without preoperative MIBI. RESULTS AND CONCLUSION: Among the 114 patients undergoing surgery, 37 had secondary hyperparathyroidism in dialysis replacement, and 77 patients had post-renal transplant persistent disease. We were successful in 107 cases with only 7 failures (93.8% of success rate). Among these failures, only one parathyroid gland was not found in 4 cases, 2 parathyroid glands were not found in 2 cases and in 1 patient the 4 glands were found but this patient remained hypercalcemic and a postoperative diagnosis of supernumerary parathyroid gland was made. Surgery for treatment of renal hyperparathyroidism proved to be an effective (93.8%) and reproductible procedure, even without MIBI. Elsevier 2020-11-16 /pmc/articles/PMC9483931/ /pubmed/33303418 http://dx.doi.org/10.1016/j.bjorl.2020.10.009 Text en © 2020 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Neves, Murilo Catafesta das
Abrahão, Augusto Riedel
Abrahão, Marcio
Rosano, Marcello
Rocha, Lillian Andrade da
Machado, Hanna Karla Andrade Guapyassu
Santos, Rodrigo Oliveira
Sestamibi scan in renal parathyroidectomy: a worthwhile preoperative exam?()
title Sestamibi scan in renal parathyroidectomy: a worthwhile preoperative exam?()
title_full Sestamibi scan in renal parathyroidectomy: a worthwhile preoperative exam?()
title_fullStr Sestamibi scan in renal parathyroidectomy: a worthwhile preoperative exam?()
title_full_unstemmed Sestamibi scan in renal parathyroidectomy: a worthwhile preoperative exam?()
title_short Sestamibi scan in renal parathyroidectomy: a worthwhile preoperative exam?()
title_sort sestamibi scan in renal parathyroidectomy: a worthwhile preoperative exam?()
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483931/
https://www.ncbi.nlm.nih.gov/pubmed/33303418
http://dx.doi.org/10.1016/j.bjorl.2020.10.009
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