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Polygenic Risk Scores in Alzheimer’s Disease Genetics: Methodology, Applications, Inclusion, and Diversity

The success of genome-wide association studies (GWAS) completed in the last 15 years has reinforced a key fact: polygenic architecture makes a substantial contribution to variation of susceptibility to complex disease, including Alzheimer’s disease. One straight-forward way to capture this architect...

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Detalles Bibliográficos
Autores principales:	Clark, Kaylyn, Leung, Yuk Yee, Lee, Wan-Ping, Voight, Benjamin, Wang, Li-San
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484091/ https://www.ncbi.nlm.nih.gov/pubmed/35848019 http://dx.doi.org/10.3233/JAD-220025

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