Cargando…

Pan-cancer analysis of genomic and transcriptomic data reveals the prognostic relevance of human proteasome genes in different cancer types

BACKGROUND: The human proteasome gene family (PSM) consists of 49 genes that play a crucial role in cancer proteostasis. However, little is known about the effect of PSM gene expression and genetic alterations on clinical outcome in different cancer forms. METHODS: Here, we performed a comprehensive...

Descripción completa

Detalles Bibliográficos
Autores principales:	Larsson, Peter, Pettersson, Daniella, Engqvist, Hanna, Werner Rönnerman, Elisabeth, Forssell-Aronsson, Eva, Kovács, Anikó, Karlsson, Per, Helou, Khalil, Parris, Toshima Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484138/ https://www.ncbi.nlm.nih.gov/pubmed/36123629 http://dx.doi.org/10.1186/s12885-022-10079-4

Ejemplares similares

Optimization of cell viability assays to improve replicability and reproducibility of cancer drug sensitivity screens
por: Larsson, Peter, et al.
Publicado: (2020)

Clonal relatedness in tumour pairs of breast cancer patients
por: Biermann, Jana, et al.
Publicado: (2018)

Genome-wide multi-omics profiling of the 8p11-p12 amplicon in breast carcinoma
por: Parris, Toshima Z., et al.
Publicado: (2018)

Validation of Novel Prognostic Biomarkers for Early-Stage Clear-Cell, Endometrioid and Mucinous Ovarian Carcinomas Using Immunohistochemistry
por: Engqvist, Hanna, et al.
Publicado: (2020)

Integrative genomics approach identifies molecular features associated with early-stage ovarian carcinoma histotypes
por: Engqvist, Hanna, et al.
Publicado: (2020)

Trefoil factor family proteins as potential diagnostic markers for mucinous invasive ovarian carcinoma
por: Werner Rönnerman, Elisabeth, et al.
Publicado: (2023)

Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas
por: Engqvist, Hanna, et al.
Publicado: (2019)

Genetic alterations associated with multiple primary malignancies
por: Nyqvist, Jenny, et al.
Publicado: (2021)

The prognostic relevance of FOXA1 and Nestin expression in breast cancer metastases: a retrospective study of 164 cases during a 10-year period (2004–2014)
por: De Lara, Shahin, et al.
Publicado: (2019)

Transcriptomic and genomic profiling of early-stage ovarian carcinomas associated with histotype and overall survival
por: Engqvist, Hanna, et al.
Publicado: (2018)

Clinical relevance of breast cancer-related genes as potential biomarkers for oral squamous cell carcinoma
por: Parris, Toshima Z, et al.
Publicado: (2014)

Distinct microRNA Expression Profiles in Mouse Renal Cortical Tissue after (177)Lu-octreotate Administration
por: Schüler, Emil, et al.
Publicado: (2014)

Potential Biomarkers for Radiation-Induced Renal Toxicity following (177)Lu-Octreotate Administration in Mice
por: Schüler, Emil, et al.
Publicado: (2015)

Pan-cancer analysis identifies BIRC5 as a prognostic biomarker
por: Fäldt Beding, Anna, et al.
Publicado: (2022)

Effects of internal low-dose irradiation from (131)I on gene expression in normal tissues in Balb/c mice
por: Schüler, Emil, et al.
Publicado: (2011)

Transcriptional response of BALB/c mouse thyroids following in vivo astatine-211 exposure reveals distinct gene expression profiles
por: Rudqvist, Nils, et al.
Publicado: (2012)

Circadian rhythm influences genome-wide transcriptional responses to (131)I in a tissue-specific manner in mice
por: Langen, Britta, et al.
Publicado: (2015)

Age-related long-term response in rat thyroid tissue and plasma after internal low dose exposure to (131)I
por: Larsson, Malin, et al.
Publicado: (2022)

Long-term transcriptomic and proteomic effects in Sprague Dawley rat thyroid and plasma after internal low dose (131)I exposure
por: Larsson, Malin, et al.
Publicado: (2020)

Correction: Long-term transcriptomic and proteomic effects in Sprague Dawley rat thyroid and plasma after internal low dose 131I exposure
por: Larsson, Malin, et al.
Publicado: (2021)

Transcriptional Response in Mouse Thyroid Tissue after (211)At Administration: Effects of Absorbed Dose, Initial Dose-Rate and Time after Administration
por: Rudqvist, Nils, et al.
Publicado: (2015)

Transcriptional response in normal mouse tissues after i.v. (211)At administration - response related to absorbed dose, dose rate, and time
por: Langen, Britta, et al.
Publicado: (2015)

Gene expression signature in mouse thyroid tissue after (131)I and (211)At exposure
por: Rudqvist, Nils, et al.
Publicado: (2015)

Transcriptional response to (131)I exposure of rat thyroid gland
por: Rudqvist, Nils, et al.
Publicado: (2017)

Hedgehog inhibitor sonidegib potentiates (177)Lu-octreotate therapy of GOT1 human small intestine neuroendocrine tumors in nude mice
por: Spetz, Johan, et al.
Publicado: (2017)

Previously diagnosed multiple primary malignancies in patients with breast carcinoma in Western Sweden between 2007 and 2018
por: Nyqvist, Jenny, et al.
Publicado: (2020)

Co-administration with A1M does not influence apoptotic response of (177)Lu-octreotate in GOT1 neuroendocrine tumors
por: Rassol, Nishte, et al.
Publicado: (2023)

Clinical relevance of biomarker discordance between primary breast cancers and synchronous axillary lymph node metastases
por: Janeva, Slavica, et al.
Publicado: (2023)

Elevated cyclin B2 expression in invasive breast carcinoma is associated with unfavorable clinical outcome
por: Shubbar, Emman, et al.
Publicado: (2013)

Up-regulation of cell cycle arrest protein BTG2 correlates with increased overall survival in breast cancer, as detected by immunohistochemistry using tissue microarray
por: Möllerström, Elin, et al.
Publicado: (2010)

Metachronous and Synchronous Occurrence of 5 Primary Malignancies in a Female Patient between 1997 and 2013: A Case Report with Germline and Somatic Genetic Analysis
por: Nyqvist, Jenny, et al.
Publicado: (2017)

Male Breast Carcinoma after Irradiation and Long-Term Phenothiazine Exposure: A Case Report
por: Hultborn, Ragnar, et al.
Publicado: (2020)

Transcriptional effects of (177)Lu-octreotate therapy using a priming treatment schedule on GOT1 tumor in nude mice
por: Spetz, Johan, et al.
Publicado: (2019)

Pan-cancer analyses of human nuclear receptors reveal transcriptome diversity and prognostic value across cancer types
por: Parris, Toshima Z.
Publicado: (2020)

Prognostic Significance of BIRC5/Survivin in Breast Cancer: Results from Three Independent Cohorts
por: Oparina, Nina, et al.
Publicado: (2021)

The IRI-DICE hypothesis: ionizing radiation-induced DSBs may have a functional role for non-deterministic responses at low doses
por: Langen, Britta, et al.
Publicado: (2020)

Priming increases the anti-tumor effect and therapeutic window of (177)Lu-octreotate in nude mice bearing human small intestine neuroendocrine tumor GOT1
por: Dalmo, Johanna, et al.
Publicado: (2017)

Clinical evaluation of molecular surrogate subtypes in patients with ipsilateral multifocal primary breast cancer
por: Janeva, Slavica, et al.
Publicado: (2023)

Comparison of breast cancer surrogate subtyping using a closed-system RT-qPCR breast cancer assay and immunohistochemistry on 100 core needle biopsies with matching surgical specimens
por: Janeva, Slavica, et al.
Publicado: (2021)

Deconvolution of expression microarray data reveals (131)I-induced responses otherwise undetected in thyroid tissue
por: Langen, Britta, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_d9n271o5jh7v2bn3hlv4rkjott