Transcription factor AP2 enhances malignancy of non-small cell lung cancer through upregulation of USP22 gene expression

BACKGROUND: Ubiquitin-specific protease 22 (USP22), a putative cancer stem cell marker, is frequently upregulated in cancers, and USP22 overexpression is associated with aggressive growth, metastasis, and therapy resistance in various human cancers including lung cancer. However, USP22 gene amplific...

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Detalles Bibliográficos
Autores principales: Sun, Ting, Zhang, Keqiang, Li, Wendong, Liu, Yunze, Pangeni, Rajendra P., Li, Aimin, Arvanitis, Leonidas, Raz, Dan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484186/
https://www.ncbi.nlm.nih.gov/pubmed/36123698
http://dx.doi.org/10.1186/s12964-022-00946-9

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