Cargando…

Micropeptide MIAC inhibits the tumor progression by interacting with AQP2 and inhibiting EREG/EGFR signaling in renal cell carcinoma

BACKGROUND: Although, micropeptides encoded by non-coding RNA have been shown to have an important role in a variety of tumors processes, there have been no reports on micropeptide in renal cell carcinoma (RCC). Based on the micropeptide MIAC (micropeptide inhibiting actin cytoskeleton) discovered a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Mengwei, Liu, Guangxiang, Jin, Xinrong, Guo, Hongqian, Setrerrahmane, Sarra, Xu, Xindi, Li, Tiantian, Lin, Yunfei, Xu, Hanmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484220/ https://www.ncbi.nlm.nih.gov/pubmed/36117171 http://dx.doi.org/10.1186/s12943-022-01654-1

Ejemplares similares

The Role of EREG/EGFR Pathway in Tumor Progression
por: Cheng, Wan-Li, et al.
Publicado: (2021)

Integrins as attractive targets for cancer therapeutics
por: Li, Meng, et al.
Publicado: (2021)

Tumor-related interleukins: old validated targets for new anti-cancer drug development
por: Setrerrahmane, Sarra, et al.
Publicado: (2017)

Trends in insulin resistance: insights into mechanisms and therapeutic strategy
por: Li, Mengwei, et al.
Publicado: (2022)

Micropeptide
por: Sousa, Maria E., et al.
Publicado: (2018)

Novel production method of innovative antiangiogenic and antitumor small peptides in Escherichia coli
por: Setrerrahmane, Sarra, et al.
Publicado: (2017)

Polymorphism in the EREG gene confers susceptibility to tuberculosis
por: Cao, Wen, et al.
Publicado: (2019)

Micropeptides translated from putative long non-coding RNAs: Micropeptides translated from lncRNAs
por: Li, Junhong, et al.
Publicado: (2022)

Accurate control of dual-receptor-engineered T cell activity through a bifunctional anti-angiogenic peptide
por: Zhang, Erhao, et al.
Publicado: (2018)

Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter
por: Qu, X, et al.
Publicado: (2016)

BMP7 and EREG Contribute to the Inductive Potential of Dental Mesenchyme
por: Gao, Bo, et al.
Publicado: (2015)

EREG is a risk factor for the prognosis of patients with cervical cancer
por: Li, Tianye, et al.
Publicado: (2023)

Lena Ho: Micropeptides under the spotlight
por: Morgado-Palacin, Lucia
Publicado: (2022)

Serum fetuin-A is associated with the components of MIAC(malnutrition, inflammation, atherosclerosis, calcification) syndrome in different stages of chronic kidney disease
por: MUTLUAY, Rüya, et al.
Publicado: (2019)

The micropeptide LEMP plays an evolutionarily conserved role in myogenesis
por: Wang, Lantian, et al.
Publicado: (2020)

Combination Therapy of PEG-HM-3 and Methotrexate Retards Adjuvant-Induced Arthritis
por: Hao, Jingchao, et al.
Publicado: (2017)

Cardiomyocyte hypertrophy induced by Endonuclease G deficiency requires reactive oxygen radicals accumulation and is inhibitable by the micropeptide humanin
por: Blasco, Natividad, et al.
Publicado: (2018)

Syringic acid mitigates isoproterenol‐induced cardiac hypertrophy and fibrosis by downregulating Ereg
por: Han, Xiongyi, et al.
Publicado: (2022)

Emerging role of long noncoding RNA-encoded micropeptides in cancer
por: Ye, Mujie, et al.
Publicado: (2020)

Minireview: Novel Micropeptide Discovery by Proteomics and Deep Sequencing Methods
por: Tharakan, Ravi, et al.
Publicado: (2021)

The difference of the retinal structural and microvascular characteristics in patients with MOGAD-ON and AQP4-ON
por: Yao, Yajun, et al.
Publicado: (2022)

Preferential Response of Basal-Like Head and Neck Squamous Cell Carcinoma Cell Lines to EGFR-Targeted Therapy Depending on EREG-Driven Oncogenic Addiction
por: Job, Sylvie, et al.
Publicado: (2019)

EREG-driven oncogenesis of Head and Neck Squamous Cell Carcinoma exhibits higher sensitivity to Erlotinib therapy
por: Liu, Shuli, et al.
Publicado: (2020)

MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation
por: Makarewich, Catherine A., et al.
Publicado: (2018)

MiPepid: MicroPeptide identification tool using machine learning
por: Zhu, Mengmeng, et al.
Publicado: (2019)

Translation and natural selection of micropeptides from long non-canonical RNAs
por: Patraquim, Pedro, et al.
Publicado: (2022)

The cardiac translational landscape reveals that micropeptides are new players involved in cardiomyocyte hypertrophy
por: Yan, Youchen, et al.
Publicado: (2021)

Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer
por: Lee, Michael S, et al.
Publicado: (2016)

RHOA GTPase Controls YAP-Mediated EREG Signaling in Small Intestinal Stem Cell Maintenance
por: Liu, Ming, et al.
Publicado: (2017)

Blocking EREG/GPX4 Sensitizes Head and Neck Cancer to Cetuximab through Ferroptosis Induction
por: Jehl, Aude, et al.
Publicado: (2023)

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age
por: Kragness, S., et al.
Publicado: (2022)

Inhibitory and stimulatory micropeptides preferentially bind to different conformations of the cardiac calcium pump
por: Cleary, Sean R., et al.
Publicado: (2022)

Functional Micropeptides Encoded by Long Non-Coding RNAs: A Comprehensive Review
por: Pan, Jianfeng, et al.
Publicado: (2022)

Transmembrane protein 170B is a novel breast tumorigenesis suppressor gene that inhibits the Wnt/β-catenin pathway
por: Li, Mengwei, et al.
Publicado: (2018)

Immunohistochemical Localization of the Aquaporins AQP1, AQP3, AQP4, and AQP5 in the Mouse Respiratory System
por: Matsuzaki, Toshiyuki, et al.
Publicado: (2009)

Viral Infection Identifies Micropeptides Differentially Regulated in smORF-Containing lncRNAs
por: Razooky, Brandon S., et al.
Publicado: (2017)

Identification of Novel Micropeptides Derived from Hepatocellular Carcinoma-Specific Long Noncoding RNA
por: Polenkowski, Mareike, et al.
Publicado: (2021)

Sight of parasitoid wasps accelerates sexual behavior and upregulates a micropeptide gene in Drosophila
por: Ebrahim, Shimaa A. M., et al.
Publicado: (2021)

Neprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides
por: Schiemann, Ronja, et al.
Publicado: (2022)

A micropeptide JunBP regulated by TGF-β promotes hepatocellular carcinoma metastasis
por: Zhang, Hongwei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_o4c5rpdb6s8d7cflk3ev6dbihu