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Treating ARID1A mutated cancers by harnessing synthetic lethality and DNA damage response

Chromatin remodeling is an essential cellular process for organizing chromatin structure into either open or close configuration at specific chromatin locations by orchestrating and modifying histone complexes. This task is responsible for fundamental cell physiology including transcription, DNA rep...

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Detalles Bibliográficos
Autores principales:	Mandal, Jayaprakash, Mandal, Prativa, Wang, Tian-Li, Shih, Ie-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484255/ https://www.ncbi.nlm.nih.gov/pubmed/36123603 http://dx.doi.org/10.1186/s12929-022-00856-5

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