Effect of initial levothyroxine dose on neurodevelopmental and growth outcomes in children with congenital hypothyroidism

OBJECTIVES: We designed a multicentre open prospective randomized trial to evaluate the risk-benefit profile of two different initial treatment schemes with levothyroxine (L-T4), 10-12.5 μg/kg/day vs 12.6-15 μg/kg/day, on growth and neurodevelopmental outcomes in children with congenital hypothyroid...

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Detalles Bibliográficos
Autores principales: Esposito, Andrea, Vigone, Maria Cristina, Polizzi, Miriam, Wasniewska, Malgorzata Gabriela, Cassio, Alessandra, Mussa, Alessandro, Gastaldi, Roberto, Di Mase, Raffaella, Vincenzi, Gaia, Pozzi, Clara, Peroni, Elena, Bravaccio, Carmela, Capalbo, Donatella, Bruzzese, Dario, Salerno, Mariacarolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484273/
https://www.ncbi.nlm.nih.gov/pubmed/36133316
http://dx.doi.org/10.3389/fendo.2022.923448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484273/
https://www.ncbi.nlm.nih.gov/pubmed/36133316
http://dx.doi.org/10.3389/fendo.2022.923448

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