Cross-species transcriptome analysis for early detection and specific therapeutic targeting of human lupus nephritis

OBJECTIVES: Patients with lupus nephritis (LN) are in urgent need for early diagnosis and therapeutic interventions targeting aberrant molecular pathways enriched in affected kidneys. METHODS: We used mRNA-sequencing in effector (spleen) and target (kidneys, brain) tissues from lupus and control mic...

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Detalles Bibliográficos
Autores principales: Frangou, Eleni, Garantziotis, Panagiotis, Grigoriou, Maria, Banos, Aggelos, Nikolopoulos, Dionysis, Pieta, Antigone, Doumas, Stavros A, Fanouriakis, Antonis, Hatzioannou, Aikaterini, Manolakou, Theodora, Alissafi, Themis, Verginis, Panayotis, Athanasiadis, Emmanouil, Dermitzakis, Emmanouil, Bertsias, George, Filia, Anastasia, Boumpas, Dimitrios T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Systemic Lupus Erythematosus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484391/
https://www.ncbi.nlm.nih.gov/pubmed/35906002
http://dx.doi.org/10.1136/annrheumdis-2021-222069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484391/
https://www.ncbi.nlm.nih.gov/pubmed/35906002
http://dx.doi.org/10.1136/annrheumdis-2021-222069

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