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Lactobacillus gallinarum modulates the gut microbiota and produces anti-cancer metabolites to protect against colorectal tumourigenesis

OBJECTIVE: Using faecal shotgun metagenomic sequencing, we identified the depletion of Lactobacillus gallinarum in patients with colorectal cancer (CRC). We aimed to determine the potential antitumourigenic role of L. gallinarum in colorectal tumourigenesis. DESIGN: The tumor-suppressive effect of L...

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Detalles Bibliográficos
Autores principales: Sugimura, Naoki, Li, Qing, Chu, Eagle Siu Hong, Lau, Harry Cheuk Hay, Fong, Winnie, Liu, Weixin, Liang, Cong, Nakatsu, Geicho, Su, Anthony Chin Yang, Coker, Olabisi Oluwabukola, Wu, William Ka Kei, Chan, Francis Ka Leung, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484392/
https://www.ncbi.nlm.nih.gov/pubmed/34937766
http://dx.doi.org/10.1136/gutjnl-2020-323951