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Implications of the Essential Role of Small Molecule Ligand Binding Pockets in Protein–Protein Interactions
[Image: see text] Protein–protein interactions (PPIs) and protein–metabolite interactions play a key role in many biochemical processes, yet they are often viewed as being independent. However, the fact that small molecule drugs have been successful in inhibiting PPIs suggests a deeper relationship...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484464/ https://www.ncbi.nlm.nih.gov/pubmed/36044742 http://dx.doi.org/10.1021/acs.jpcb.2c04525 |