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Chimeric DNA byproducts in strand displacement amplification using the T7 replisome
Recent advances in next generation sequencing technologies enable reading DNA molecules hundreds of kilobases in length and motivate development of DNA amplification methods capable of producing long amplicons. In vivo, DNA replication is performed not by a single polymerase enzyme, but multiprotein...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484634/ https://www.ncbi.nlm.nih.gov/pubmed/36121810 http://dx.doi.org/10.1371/journal.pone.0273979 |