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Chimeric DNA byproducts in strand displacement amplification using the T7 replisome

Recent advances in next generation sequencing technologies enable reading DNA molecules hundreds of kilobases in length and motivate development of DNA amplification methods capable of producing long amplicons. In vivo, DNA replication is performed not by a single polymerase enzyme, but multiprotein...

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Detalles Bibliográficos
Autores principales: Nye, Dillon B., Tanner, Nathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484634/
https://www.ncbi.nlm.nih.gov/pubmed/36121810
http://dx.doi.org/10.1371/journal.pone.0273979

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