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A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient

INTRODUCTION. Saprochaete capitata is an emerging opportunistic fungus that is responsible for an uncommon mycosis known as geotrichosis, mainly reported in patients with haematological malignancies. It is a life-threatening condition associated with a high mortality rate of over 52 %. S. capitata m...

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Detalles Bibliográficos
Autores principales: Nachate, Soumia, Abbassi, Saloua, Elfouar, Hajar, Zouine, Yousra, Cherif Idrissi El Ganouni, Najat, Tassi, Noura, El Hakkouni, Awatif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484660/
https://www.ncbi.nlm.nih.gov/pubmed/36133179
http://dx.doi.org/10.1099/acmi.0.000450
Descripción
Sumario:INTRODUCTION. Saprochaete capitata is an emerging opportunistic fungus that is responsible for an uncommon mycosis known as geotrichosis, mainly reported in patients with haematological malignancies. It is a life-threatening condition associated with a high mortality rate of over 52 %. S. capitata may affect any organ, with a predilection for the lungs. CASE PRESENTATION. Here we report a case of pulmonary geotrichosis in a neutropenic HIV-infected patient with a prior history of treated tuberculosis. The main risk factor for pulmonary geotrichosis is profound and prolonged neutropenia. To our knowledge, this is the first reported case of S. capitata infection occurring on top of probable active miliary tuberculosis. CONCLUSION. The clinical and radiological features are non-specific and similar to those of other pulmonary fungal diseases, hence the importance of mycological examination to confirm the diagnosis. Through this report, we urge clinicians to vigilantly consider S. capitata as an aetiological agent in the differential diagnosis of fungal infections in HIV-infected individuals and to routinely screen for associated infections.