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A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient
INTRODUCTION. Saprochaete capitata is an emerging opportunistic fungus that is responsible for an uncommon mycosis known as geotrichosis, mainly reported in patients with haematological malignancies. It is a life-threatening condition associated with a high mortality rate of over 52 %. S. capitata m...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484660/ https://www.ncbi.nlm.nih.gov/pubmed/36133179 http://dx.doi.org/10.1099/acmi.0.000450 |
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author | Nachate, Soumia Abbassi, Saloua Elfouar, Hajar Zouine, Yousra Cherif Idrissi El Ganouni, Najat Tassi, Noura El Hakkouni, Awatif |
author_facet | Nachate, Soumia Abbassi, Saloua Elfouar, Hajar Zouine, Yousra Cherif Idrissi El Ganouni, Najat Tassi, Noura El Hakkouni, Awatif |
author_sort | Nachate, Soumia |
collection | PubMed |
description | INTRODUCTION. Saprochaete capitata is an emerging opportunistic fungus that is responsible for an uncommon mycosis known as geotrichosis, mainly reported in patients with haematological malignancies. It is a life-threatening condition associated with a high mortality rate of over 52 %. S. capitata may affect any organ, with a predilection for the lungs. CASE PRESENTATION. Here we report a case of pulmonary geotrichosis in a neutropenic HIV-infected patient with a prior history of treated tuberculosis. The main risk factor for pulmonary geotrichosis is profound and prolonged neutropenia. To our knowledge, this is the first reported case of S. capitata infection occurring on top of probable active miliary tuberculosis. CONCLUSION. The clinical and radiological features are non-specific and similar to those of other pulmonary fungal diseases, hence the importance of mycological examination to confirm the diagnosis. Through this report, we urge clinicians to vigilantly consider S. capitata as an aetiological agent in the differential diagnosis of fungal infections in HIV-infected individuals and to routinely screen for associated infections. |
format | Online Article Text |
id | pubmed-9484660 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Microbiology Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-94846602022-09-20 A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient Nachate, Soumia Abbassi, Saloua Elfouar, Hajar Zouine, Yousra Cherif Idrissi El Ganouni, Najat Tassi, Noura El Hakkouni, Awatif Access Microbiol Case Reports INTRODUCTION. Saprochaete capitata is an emerging opportunistic fungus that is responsible for an uncommon mycosis known as geotrichosis, mainly reported in patients with haematological malignancies. It is a life-threatening condition associated with a high mortality rate of over 52 %. S. capitata may affect any organ, with a predilection for the lungs. CASE PRESENTATION. Here we report a case of pulmonary geotrichosis in a neutropenic HIV-infected patient with a prior history of treated tuberculosis. The main risk factor for pulmonary geotrichosis is profound and prolonged neutropenia. To our knowledge, this is the first reported case of S. capitata infection occurring on top of probable active miliary tuberculosis. CONCLUSION. The clinical and radiological features are non-specific and similar to those of other pulmonary fungal diseases, hence the importance of mycological examination to confirm the diagnosis. Through this report, we urge clinicians to vigilantly consider S. capitata as an aetiological agent in the differential diagnosis of fungal infections in HIV-infected individuals and to routinely screen for associated infections. Microbiology Society 2022-08-25 /pmc/articles/PMC9484660/ /pubmed/36133179 http://dx.doi.org/10.1099/acmi.0.000450 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial License. The Microbiology Society waived the open access fees for this article. |
spellingShingle | Case Reports Nachate, Soumia Abbassi, Saloua Elfouar, Hajar Zouine, Yousra Cherif Idrissi El Ganouni, Najat Tassi, Noura El Hakkouni, Awatif A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient |
title | A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient |
title_full | A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient |
title_fullStr | A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient |
title_full_unstemmed | A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient |
title_short | A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient |
title_sort | case of saprochaete capitata pulmonary infection in a neutropenic hiv-infected patient |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484660/ https://www.ncbi.nlm.nih.gov/pubmed/36133179 http://dx.doi.org/10.1099/acmi.0.000450 |
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