Cargando…

A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient

INTRODUCTION. Saprochaete capitata is an emerging opportunistic fungus that is responsible for an uncommon mycosis known as geotrichosis, mainly reported in patients with haematological malignancies. It is a life-threatening condition associated with a high mortality rate of over 52 %. S. capitata m...

Descripción completa

Detalles Bibliográficos
Autores principales: Nachate, Soumia, Abbassi, Saloua, Elfouar, Hajar, Zouine, Yousra, Cherif Idrissi El Ganouni, Najat, Tassi, Noura, El Hakkouni, Awatif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484660/
https://www.ncbi.nlm.nih.gov/pubmed/36133179
http://dx.doi.org/10.1099/acmi.0.000450
_version_ 1784791920722051072
author Nachate, Soumia
Abbassi, Saloua
Elfouar, Hajar
Zouine, Yousra
Cherif Idrissi El Ganouni, Najat
Tassi, Noura
El Hakkouni, Awatif
author_facet Nachate, Soumia
Abbassi, Saloua
Elfouar, Hajar
Zouine, Yousra
Cherif Idrissi El Ganouni, Najat
Tassi, Noura
El Hakkouni, Awatif
author_sort Nachate, Soumia
collection PubMed
description INTRODUCTION. Saprochaete capitata is an emerging opportunistic fungus that is responsible for an uncommon mycosis known as geotrichosis, mainly reported in patients with haematological malignancies. It is a life-threatening condition associated with a high mortality rate of over 52 %. S. capitata may affect any organ, with a predilection for the lungs. CASE PRESENTATION. Here we report a case of pulmonary geotrichosis in a neutropenic HIV-infected patient with a prior history of treated tuberculosis. The main risk factor for pulmonary geotrichosis is profound and prolonged neutropenia. To our knowledge, this is the first reported case of S. capitata infection occurring on top of probable active miliary tuberculosis. CONCLUSION. The clinical and radiological features are non-specific and similar to those of other pulmonary fungal diseases, hence the importance of mycological examination to confirm the diagnosis. Through this report, we urge clinicians to vigilantly consider S. capitata as an aetiological agent in the differential diagnosis of fungal infections in HIV-infected individuals and to routinely screen for associated infections.
format Online
Article
Text
id pubmed-9484660
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Microbiology Society
record_format MEDLINE/PubMed
spelling pubmed-94846602022-09-20 A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient Nachate, Soumia Abbassi, Saloua Elfouar, Hajar Zouine, Yousra Cherif Idrissi El Ganouni, Najat Tassi, Noura El Hakkouni, Awatif Access Microbiol Case Reports INTRODUCTION. Saprochaete capitata is an emerging opportunistic fungus that is responsible for an uncommon mycosis known as geotrichosis, mainly reported in patients with haematological malignancies. It is a life-threatening condition associated with a high mortality rate of over 52 %. S. capitata may affect any organ, with a predilection for the lungs. CASE PRESENTATION. Here we report a case of pulmonary geotrichosis in a neutropenic HIV-infected patient with a prior history of treated tuberculosis. The main risk factor for pulmonary geotrichosis is profound and prolonged neutropenia. To our knowledge, this is the first reported case of S. capitata infection occurring on top of probable active miliary tuberculosis. CONCLUSION. The clinical and radiological features are non-specific and similar to those of other pulmonary fungal diseases, hence the importance of mycological examination to confirm the diagnosis. Through this report, we urge clinicians to vigilantly consider S. capitata as an aetiological agent in the differential diagnosis of fungal infections in HIV-infected individuals and to routinely screen for associated infections. Microbiology Society 2022-08-25 /pmc/articles/PMC9484660/ /pubmed/36133179 http://dx.doi.org/10.1099/acmi.0.000450 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial License. The Microbiology Society waived the open access fees for this article.
spellingShingle Case Reports
Nachate, Soumia
Abbassi, Saloua
Elfouar, Hajar
Zouine, Yousra
Cherif Idrissi El Ganouni, Najat
Tassi, Noura
El Hakkouni, Awatif
A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient
title A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient
title_full A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient
title_fullStr A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient
title_full_unstemmed A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient
title_short A case of Saprochaete capitata pulmonary infection in a neutropenic HIV-infected patient
title_sort case of saprochaete capitata pulmonary infection in a neutropenic hiv-infected patient
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484660/
https://www.ncbi.nlm.nih.gov/pubmed/36133179
http://dx.doi.org/10.1099/acmi.0.000450
work_keys_str_mv AT nachatesoumia acaseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT abbassisaloua acaseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT elfouarhajar acaseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT zouineyousra acaseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT cherifidrissielganouninajat acaseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT tassinoura acaseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT elhakkouniawatif acaseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT nachatesoumia caseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT abbassisaloua caseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT elfouarhajar caseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT zouineyousra caseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT cherifidrissielganouninajat caseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT tassinoura caseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient
AT elhakkouniawatif caseofsaprochaetecapitatapulmonaryinfectioninaneutropenichivinfectedpatient