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Automated prediction of site and sequence of protein modification with ATRP initiators

One of the most straightforward and commonly used chemical modifications of proteins is to react surface amino groups (lysine residues) with activated esters. This chemistry has been used to generate protein-polymer conjugates, many of which are now approved therapeutics. Similar conjugates have als...

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Detalles Bibliográficos
Autores principales: Patel, Arth, Smith, Paige N., Russell, Alan J., Carmali, Sheiliza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484671/
https://www.ncbi.nlm.nih.gov/pubmed/36121820
http://dx.doi.org/10.1371/journal.pone.0274606