Identification of a BAZ2A Bromodomain Hit Compound by Fragment Joining

[Image: see text] The bromodomains of BAZ2A and BAZ2B (bromodomain adjacent to zinc finger domain proteins 2) are among the most hard to drug of the 61 human bromodomains. While little is known about the role of BAZ2B, there is strong evidence for the opportunity of targeting BAZ2A in various cancer...

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Detalles Bibliográficos
Autores principales: Dalle Vedove, Andrea, Cazzanelli, Giulia, Corsi, Jessica, Sedykh, Maria, D’Agostino, Vito Giuseppe, Caflisch, Amedeo, Lolli, Graziano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484724/
https://www.ncbi.nlm.nih.gov/pubmed/36147311
http://dx.doi.org/10.1021/acsbiomedchemau.1c00016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484724/
https://www.ncbi.nlm.nih.gov/pubmed/36147311
http://dx.doi.org/10.1021/acsbiomedchemau.1c00016

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