Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa

The alternative (noncanonical) nuclear factor-κB (NF-κB) signaling pathway predominantly regulates the function of the p52/RelB heterodimer. Germline Nfkb2 deficiency in mice leads to loss of p100/p52 protein and offers protection against a variety of gastrointestinal conditions, including azoxymeth...

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Detalles Bibliográficos
Autores principales: Papoutsopoulou, Stamatia, Tang, Joseph, Elramli, Ahmed H., Williams, Jonathan M., Gupta, Nitika, Ikuomola, Felix I., Sheibani-Tezerji, Raheleh, Alam, Mohammad T., Hernández-Fernaud, Juan R., Caamaño, Jorge H., Probert, Chris S., Muller, Werner, Duckworth, Carrie A., Pritchard, D. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485003/
https://www.ncbi.nlm.nih.gov/pubmed/35916405
http://dx.doi.org/10.1152/ajpgi.00037.2022

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