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Value Set for the EQ-5D-Y-3L in Hungary
BACKGROUND: The Hungarian health technology assessment guidelines recommend the use of the EuroQol instrument family in quality-adjusted life-year calculations. However, no national value set exists for the EQ-5D-Y-3L or any other youth-specific instrument. OBJECTIVE: This study aims to develop a na...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485017/ https://www.ncbi.nlm.nih.gov/pubmed/36123448 http://dx.doi.org/10.1007/s40273-022-01190-2 |
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author | Rencz, Fanni Ruzsa, Gábor Bató, Alex Yang, Zhihao Finch, Aureliano Paolo Brodszky, Valentin |
author_facet | Rencz, Fanni Ruzsa, Gábor Bató, Alex Yang, Zhihao Finch, Aureliano Paolo Brodszky, Valentin |
author_sort | Rencz, Fanni |
collection | PubMed |
description | BACKGROUND: The Hungarian health technology assessment guidelines recommend the use of the EuroQol instrument family in quality-adjusted life-year calculations. However, no national value set exists for the EQ-5D-Y-3L or any other youth-specific instrument. OBJECTIVE: This study aims to develop a national value set of the EQ-5D-Y-3L for Hungary based on preferences of the general adult population. METHODS: This study followed the international valuation protocol for the EQ-5D-Y-3L. Two independent samples, representative of the Hungarian general adult population in terms of age and sex were recruited to complete online discrete choice experiment (DCE) tasks and composite time trade-off (cTTO) tasks by computer-assisted personal interviews. Adults valued hypothetical EQ-5D-Y-3L health states considering the health of a 10-year-old child. DCE data were modelled using a mixed logit model with random-correlated coefficients. Latent DCE utility estimates were mapped onto mean observed cTTO utilities using ordinary least squares regression. RESULTS: Overall, 996 and 200 respondents completed the DCE and cTTO surveys, respectively. For each domain, the value set resulted in larger utility decrements with more severe response levels. The relative importance of domains by level 3 coefficients was as follows: having pain or discomfort > feeling worried, sad or unhappy > mobility > doing usual activities > looking after myself. Overall, 12.3% of all health states had negative utilities in the value set, with the worst health state having the lowest predicted utility of − 0.485. CONCLUSION: This study developed a national value set of the EQ-5D-Y-3L for Hungary. The value set enables to evaluate the cost utility of health technologies for children and adolescents based on societal preferences in Hungary. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40273-022-01190-2. |
format | Online Article Text |
id | pubmed-9485017 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-94850172022-09-21 Value Set for the EQ-5D-Y-3L in Hungary Rencz, Fanni Ruzsa, Gábor Bató, Alex Yang, Zhihao Finch, Aureliano Paolo Brodszky, Valentin Pharmacoeconomics Original Research Article BACKGROUND: The Hungarian health technology assessment guidelines recommend the use of the EuroQol instrument family in quality-adjusted life-year calculations. However, no national value set exists for the EQ-5D-Y-3L or any other youth-specific instrument. OBJECTIVE: This study aims to develop a national value set of the EQ-5D-Y-3L for Hungary based on preferences of the general adult population. METHODS: This study followed the international valuation protocol for the EQ-5D-Y-3L. Two independent samples, representative of the Hungarian general adult population in terms of age and sex were recruited to complete online discrete choice experiment (DCE) tasks and composite time trade-off (cTTO) tasks by computer-assisted personal interviews. Adults valued hypothetical EQ-5D-Y-3L health states considering the health of a 10-year-old child. DCE data were modelled using a mixed logit model with random-correlated coefficients. Latent DCE utility estimates were mapped onto mean observed cTTO utilities using ordinary least squares regression. RESULTS: Overall, 996 and 200 respondents completed the DCE and cTTO surveys, respectively. For each domain, the value set resulted in larger utility decrements with more severe response levels. The relative importance of domains by level 3 coefficients was as follows: having pain or discomfort > feeling worried, sad or unhappy > mobility > doing usual activities > looking after myself. Overall, 12.3% of all health states had negative utilities in the value set, with the worst health state having the lowest predicted utility of − 0.485. CONCLUSION: This study developed a national value set of the EQ-5D-Y-3L for Hungary. The value set enables to evaluate the cost utility of health technologies for children and adolescents based on societal preferences in Hungary. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40273-022-01190-2. Springer International Publishing 2022-09-20 2022 /pmc/articles/PMC9485017/ /pubmed/36123448 http://dx.doi.org/10.1007/s40273-022-01190-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Original Research Article Rencz, Fanni Ruzsa, Gábor Bató, Alex Yang, Zhihao Finch, Aureliano Paolo Brodszky, Valentin Value Set for the EQ-5D-Y-3L in Hungary |
title | Value Set for the EQ-5D-Y-3L in Hungary |
title_full | Value Set for the EQ-5D-Y-3L in Hungary |
title_fullStr | Value Set for the EQ-5D-Y-3L in Hungary |
title_full_unstemmed | Value Set for the EQ-5D-Y-3L in Hungary |
title_short | Value Set for the EQ-5D-Y-3L in Hungary |
title_sort | value set for the eq-5d-y-3l in hungary |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485017/ https://www.ncbi.nlm.nih.gov/pubmed/36123448 http://dx.doi.org/10.1007/s40273-022-01190-2 |
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