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Enhanced tryptophan-kynurenine metabolism via indoleamine 2,3-dioxygenase 1 induction in dermatomyositis

OBJECTIVES: Extrahepatic tryptophan (Trp)-kynurenine (Kyn) metabolism via indoleamine 2,3-dioxygenase 1 (IDO1) induction was found to be associated with intrinsic immune regulation. However, the Trp-Kyn metabolism–associated immune regulation in dermatomyositis (DM) remains unknown. Therefore, we ai...

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Detalles Bibliográficos
Autores principales: Wu, Dan, Chen, Mengya, Chen, Shile, Zhang, Shimin, Chen, Yongheng, Zhao, Qian, Xue, Ke, Xue, Feng, Chen, Xiaosong, Zhou, Min, Li, Hao, Zheng, Jie, Le, Yunchen, Cao, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485101/
https://www.ncbi.nlm.nih.gov/pubmed/35778590
http://dx.doi.org/10.1007/s10067-022-06263-3