CAF-derived exosomal WEE2-AS1 facilitates colorectal cancer progression via promoting degradation of MOB1A to inhibit the Hippo pathway

Cancer-associated fibroblasts (CAFs) are the most abundant stromal components in the tumor microenvironment (TME) and closely involved in tumor progression. However, the precise biological functions and molecular mechanisms of CAFs in the TME have yet to be understood. Here, we demonstrate that WEE2...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Peng, Zhang, Dongsheng, Wang, Tuo, Ji, Jiangzhou, Jin, Chi, Peng, Chaofan, Tan, Yuqian, Zhou, Jiahui, Wang, Lu, Feng, Yifei, Sun, Yueming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485119/
https://www.ncbi.nlm.nih.gov/pubmed/36123327
http://dx.doi.org/10.1038/s41419-022-05240-7

Ejemplares similares

Ejemplares similares