Intranuclear cardiac troponin I plays a functional role in regulating Atp2a2 expression in cardiomyocytes

In the past studies, it is shown that cardiac troponin I (cTnI, encoded by TNNI3), as a cytoplasmic protein, is an inhibitory subunit in troponin complex, and involves in cardiomyocyte diastolic regulation. Here, we assessed a novel role of cTnI as a nucleoprotein. Firstly, the nuclear translocation...

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Detalles Bibliográficos
Autores principales: Lu, Qian, Pan, Bo, Bai, Haobo, Zhao, Weian, Liu, Lingjuan, Li, Gu, Liu, Ruimin, Lv, Tiewei, Huang, Xupei, Li, Xi, Tian, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485201/
https://www.ncbi.nlm.nih.gov/pubmed/36157491
http://dx.doi.org/10.1016/j.gendis.2021.04.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485201/
https://www.ncbi.nlm.nih.gov/pubmed/36157491
http://dx.doi.org/10.1016/j.gendis.2021.04.007

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