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Intranuclear cardiac troponin I plays a functional role in regulating Atp2a2 expression in cardiomyocytes
In the past studies, it is shown that cardiac troponin I (cTnI, encoded by TNNI3), as a cytoplasmic protein, is an inhibitory subunit in troponin complex, and involves in cardiomyocyte diastolic regulation. Here, we assessed a novel role of cTnI as a nucleoprotein. Firstly, the nuclear translocation...
Autores principales: | Lu, Qian, Pan, Bo, Bai, Haobo, Zhao, Weian, Liu, Lingjuan, Li, Gu, Liu, Ruimin, Lv, Tiewei, Huang, Xupei, Li, Xi, Tian, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485201/ https://www.ncbi.nlm.nih.gov/pubmed/36157491 http://dx.doi.org/10.1016/j.gendis.2021.04.007 |
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