Cargando…
Chaperone-assisted E3 ligase CHIP: A double agent in cancer
The carboxy-terminus of Hsp70-interacting protein (CHIP) is a ubiquitin ligase and co-chaperone belonging to Ubox family that plays a crucial role in the maintenance of cellular homeostasis by switching the equilibrium of the folding-refolding mechanism towards the proteasomal or lysosomal degradati...
Autores principales: | Kumar, Sunny, Basu, Malini, Ghosh, Mrinal K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485218/ https://www.ncbi.nlm.nih.gov/pubmed/36157498 http://dx.doi.org/10.1016/j.gendis.2021.08.003 |
Ejemplares similares
-
The E3 Ligase CHIP: Insights into Its Structure and Regulation
por: Paul, Indranil, et al.
Publicado: (2014) -
Tumor Suppressors Having Oncogenic Functions: The Double Agents
por: Datta, Neerajana, et al.
Publicado: (2020) -
Conserved and Unique Roles of Chaperone-Dependent E3 Ubiquitin Ligase CHIP in Plants
por: Zhang, Yan, et al.
Publicado: (2021) -
Structural Basis for Chaperone‐Independent Ubiquitination of Tau Protein by Its E3 Ligase CHIP
por: Munari, Francesca, et al.
Publicado: (2022) -
Chaperone-E3 Ligase Complex HSP70-CHIP Mediates Ubiquitination of Ribosomal Protein S3
por: Hwang, Inwoo, et al.
Publicado: (2018)