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Asymmetric chromatin retention and nuclear envelopes separate chromosomes in fused cells in vivo

Hybrid cells derived through fertilization or somatic cell fusion recognize and separate chromosomes of different origins. The underlying mechanisms are unknown but could prevent aneuploidy and tumor formation. Here, we acutely induce fusion between Drosophila neural stem cells (neuroblasts; NBs) an...

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Detalles Bibliográficos
Autores principales: Sunchu, Bharath, Lee, Nicole MynYi, Taylor, Jennifer A., Segura, Roberto Carlos, Roubinet, Chantal, Cabernard, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485224/
https://www.ncbi.nlm.nih.gov/pubmed/36123528
http://dx.doi.org/10.1038/s42003-022-03874-z