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Homoharringtonine demonstrates a cytotoxic effect against triple-negative breast cancer cell lines and acts synergistically with paclitaxel
The lack of targeted therapies for triple-negative breast cancer (TNBC) contributes to their high mortality rates and high risk of relapse compared to other subtypes of breast cancer. Most TNBCs (75%) have downregulated the expression of CREB3L1 (cAMP-responsive element binding protein 3 like 1), a...
Autores principales: | Plett, Riley, Mellor, Paul, Kendall, Stephanie, Hammond, S. Austin, Boulet, Aren, Plaza, Kristine, Vizeacoumar, Frederick S., Vizeacoumar, Franco J., Anderson, Deborah H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485251/ https://www.ncbi.nlm.nih.gov/pubmed/36123435 http://dx.doi.org/10.1038/s41598-022-19621-7 |
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