ER-stress-induced secretion of circulating glucose-regulated protein 78kDa (GRP78) ameliorates pulmonary artery smooth muscle cell remodelling

Pulmonary arterial hypertension (PAH) is driven by vascular remodelling due to inflammation and cellular stress, including endoplasmic reticulum stress (ER stress). The main ER-stress chaperone, glucose-regulated protein 78 kDa (GRP78), is known to have protective effects in inflammatory diseases th...

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Detalles Bibliográficos
Autores principales: Al Zaidi, Muntadher, Pizarro, Carmen, Bley, Carolin, Repges, Elena, Sedaghat, Alexander, Zimmer, Sebastian, Jansen, Felix, Tiyerili, Vedat, Nickenig, Georg, Skowasch, Dirk, Aksoy, Adem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485380/
https://www.ncbi.nlm.nih.gov/pubmed/36029373
http://dx.doi.org/10.1007/s12192-022-01292-y

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