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Exercise inhibits JNK pathway activation and lipotoxicity via macrophage migration inhibitory factor in nonalcoholic fatty liver disease

The macrophage migration inhibitory factor (MIF) expressed in hepatocytes can limit steatosis during obesity. Lipotoxicity in nonalcoholic fatty liver disease is mediated in part by the activation of the stress kinase JNK, but whether MIF modulates JNK in lipotoxicity is unknown. In this study, we i...

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Detalles Bibliográficos
Autores principales:	Cui, Ni, Li, Hui, Dun, Yaoshan, Ripley-Gonzalez, Jeffrey W., You, Baiyang, Li, Dezhao, Liu, Yuan, Qiu, Ling, Li, Cui, Liu, Suixin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485555/ https://www.ncbi.nlm.nih.gov/pubmed/36147562 http://dx.doi.org/10.3389/fendo.2022.961231

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