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ECMO in neonates: The association between cerebral hemodynamics with neurological function

Extracorporeal membrane oxygenation (ECMO) is a superior life support technology, commonly employed in critical patients with severe respiratory or hemodynamic failure to provide effective respiratory and circulatory support, which is especially recommended for the treatment of critical neonates. Ho...

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Autores principales: Yu, Shu-Han, Mao, Dan-Hua, Ju, Rong, Fu, Yi-Yong, Zhang, Li-Bing, Yue, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485612/
https://www.ncbi.nlm.nih.gov/pubmed/36147805
http://dx.doi.org/10.3389/fped.2022.908861
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author Yu, Shu-Han
Mao, Dan-Hua
Ju, Rong
Fu, Yi-Yong
Zhang, Li-Bing
Yue, Guang
author_facet Yu, Shu-Han
Mao, Dan-Hua
Ju, Rong
Fu, Yi-Yong
Zhang, Li-Bing
Yue, Guang
author_sort Yu, Shu-Han
collection PubMed
description Extracorporeal membrane oxygenation (ECMO) is a superior life support technology, commonly employed in critical patients with severe respiratory or hemodynamic failure to provide effective respiratory and circulatory support, which is especially recommended for the treatment of critical neonates. However, the vascular management of neonates with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is still under controversy. Reconstruction or ligation for the right common carotid artery (RCCA) after ECMO is inconclusive. This review summarized the existed studies on hemodynamics and neurological function after vascular ligation or reconstruction hoping to provide better strategies for vessel management in newborns after ECMO. After reconstruction, the right cerebral blood flow can increase immediately, and the normal blood supply can be restored rapidly. But the reconstructed vessel may be occluded and stenotic in long-term follow-ups. Ligation may cause lateralization damage, but there could be no significant effect owing to the establishment of collateral circulation. The completion of the circle of Willis, the congenital anomalies of cerebral or cervical vasculature, the duration of ECMO, and the vascular condition at the site of arterial catheterization should be assessed carefully before making the decision. It is also necessary to follow up on the reconstructed vessel sustainability, and the association between cerebral hemodynamics and neurological function requires further large-scale multi-center studies.
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spelling pubmed-94856122022-09-21 ECMO in neonates: The association between cerebral hemodynamics with neurological function Yu, Shu-Han Mao, Dan-Hua Ju, Rong Fu, Yi-Yong Zhang, Li-Bing Yue, Guang Front Pediatr Pediatrics Extracorporeal membrane oxygenation (ECMO) is a superior life support technology, commonly employed in critical patients with severe respiratory or hemodynamic failure to provide effective respiratory and circulatory support, which is especially recommended for the treatment of critical neonates. However, the vascular management of neonates with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is still under controversy. Reconstruction or ligation for the right common carotid artery (RCCA) after ECMO is inconclusive. This review summarized the existed studies on hemodynamics and neurological function after vascular ligation or reconstruction hoping to provide better strategies for vessel management in newborns after ECMO. After reconstruction, the right cerebral blood flow can increase immediately, and the normal blood supply can be restored rapidly. But the reconstructed vessel may be occluded and stenotic in long-term follow-ups. Ligation may cause lateralization damage, but there could be no significant effect owing to the establishment of collateral circulation. The completion of the circle of Willis, the congenital anomalies of cerebral or cervical vasculature, the duration of ECMO, and the vascular condition at the site of arterial catheterization should be assessed carefully before making the decision. It is also necessary to follow up on the reconstructed vessel sustainability, and the association between cerebral hemodynamics and neurological function requires further large-scale multi-center studies. Frontiers Media S.A. 2022-09-06 /pmc/articles/PMC9485612/ /pubmed/36147805 http://dx.doi.org/10.3389/fped.2022.908861 Text en Copyright © 2022 Yu, Mao, Ju, Fu, Zhang and Yue. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Yu, Shu-Han
Mao, Dan-Hua
Ju, Rong
Fu, Yi-Yong
Zhang, Li-Bing
Yue, Guang
ECMO in neonates: The association between cerebral hemodynamics with neurological function
title ECMO in neonates: The association between cerebral hemodynamics with neurological function
title_full ECMO in neonates: The association between cerebral hemodynamics with neurological function
title_fullStr ECMO in neonates: The association between cerebral hemodynamics with neurological function
title_full_unstemmed ECMO in neonates: The association between cerebral hemodynamics with neurological function
title_short ECMO in neonates: The association between cerebral hemodynamics with neurological function
title_sort ecmo in neonates: the association between cerebral hemodynamics with neurological function
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485612/
https://www.ncbi.nlm.nih.gov/pubmed/36147805
http://dx.doi.org/10.3389/fped.2022.908861
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