A cyclic adenosine monophosphate response element-binding protein inhibitor enhances the antibacterial activity of polymyxin B by inhibiting the ATP hydrolyzation activity of CrrB

The emergence of polymyxin B (PB) resistant Gram-negative bacteria poses an important clinical and public health threat. Antibiotic adjuvants development is a complementary strategy that fills the gap in new antibiotics. Here, we described the discovery of the enhancement capacity of compound 666-15...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Zhang, Jinyong, He, Yuzhang, Hu, Chunxia, Cheng, Shumin, Zeng, Huan, Zheng, Manling, Yu, Huijuan, Liu, Xue, Zou, Quanming, Cui, Ruiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485624/
https://www.ncbi.nlm.nih.gov/pubmed/36147339
http://dx.doi.org/10.3389/fphar.2022.949869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485624/
https://www.ncbi.nlm.nih.gov/pubmed/36147339
http://dx.doi.org/10.3389/fphar.2022.949869

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