Triglyceride lipolysis triggers liquid crystalline phases in lipid droplets and alters the LD proteome

Lipid droplets (LDs) are reservoirs for triglycerides (TGs) and sterol-esters (SEs), but how these lipids are organized within LDs and influence their proteome remain unclear. Using in situ cryo-electron tomography, we show that glucose restriction triggers lipid phase transitions within LDs generat...

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Detalles Bibliográficos
Autores principales: Rogers, Sean, Gui, Long, Kovalenko, Anastasiia, Zoni, Valeria, Carpentier, Maxime, Ramji, Kamran, Ben Mbarek, Kalthoum, Bacle, Amelie, Fuchs, Patrick, Campomanes, Pablo, Reetz, Evan, Speer, Natalie Ortiz, Reynolds, Emma, Thiam, Abdou Rachid, Vanni, Stefano, Nicastro, Daniela, Henne, W. Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485706/
https://www.ncbi.nlm.nih.gov/pubmed/36112368
http://dx.doi.org/10.1083/jcb.202205053

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