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Daily online contouring and re-planning versus translation-only correction in neurovascular-sparing magnetic resonance-guided radiotherapy for localized prostate cancer

Neurovascular bundle (NVB) and internal pudendal artery (IPA) sparing during magnetic resonance-guided radiotherapy (MRgRT) for prostate cancer aims for preservation of erectile function. Our present workflow involves daily online contouring and re-planning on a 1.5 T MR-linac, as alternative to con...

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Autores principales: Teunissen, Frederik R., van der Voort van Zyp, Jochem R.N., de Groot-van Breugel, Eline N., Verkooijen, Helena M., Wortel, Ruud C., de Boer, Johannes C.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485897/
https://www.ncbi.nlm.nih.gov/pubmed/36148156
http://dx.doi.org/10.1016/j.phro.2022.09.002
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author Teunissen, Frederik R.
van der Voort van Zyp, Jochem R.N.
de Groot-van Breugel, Eline N.
Verkooijen, Helena M.
Wortel, Ruud C.
de Boer, Johannes C.J.
author_facet Teunissen, Frederik R.
van der Voort van Zyp, Jochem R.N.
de Groot-van Breugel, Eline N.
Verkooijen, Helena M.
Wortel, Ruud C.
de Boer, Johannes C.J.
author_sort Teunissen, Frederik R.
collection PubMed
description Neurovascular bundle (NVB) and internal pudendal artery (IPA) sparing during magnetic resonance-guided radiotherapy (MRgRT) for prostate cancer aims for preservation of erectile function. Our present workflow involves daily online contouring and re-planning on a 1.5 T MR-linac, as alternative to conventional (rigid) translation-only corrections of the prostate. We compared planned dose for the NVB and IPA between strategies. Total planned dose was significantly lower with daily online contouring and re-planning for the NVB, but not for the IPA. For the NVB and IPA, the intrapatient difference between highest and lowest fraction dose was significantly smaller for the contouring and re-planning plans.
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spelling pubmed-94858972022-09-21 Daily online contouring and re-planning versus translation-only correction in neurovascular-sparing magnetic resonance-guided radiotherapy for localized prostate cancer Teunissen, Frederik R. van der Voort van Zyp, Jochem R.N. de Groot-van Breugel, Eline N. Verkooijen, Helena M. Wortel, Ruud C. de Boer, Johannes C.J. Phys Imaging Radiat Oncol Technical Note Neurovascular bundle (NVB) and internal pudendal artery (IPA) sparing during magnetic resonance-guided radiotherapy (MRgRT) for prostate cancer aims for preservation of erectile function. Our present workflow involves daily online contouring and re-planning on a 1.5 T MR-linac, as alternative to conventional (rigid) translation-only corrections of the prostate. We compared planned dose for the NVB and IPA between strategies. Total planned dose was significantly lower with daily online contouring and re-planning for the NVB, but not for the IPA. For the NVB and IPA, the intrapatient difference between highest and lowest fraction dose was significantly smaller for the contouring and re-planning plans. Elsevier 2022-09-13 /pmc/articles/PMC9485897/ /pubmed/36148156 http://dx.doi.org/10.1016/j.phro.2022.09.002 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Technical Note
Teunissen, Frederik R.
van der Voort van Zyp, Jochem R.N.
de Groot-van Breugel, Eline N.
Verkooijen, Helena M.
Wortel, Ruud C.
de Boer, Johannes C.J.
Daily online contouring and re-planning versus translation-only correction in neurovascular-sparing magnetic resonance-guided radiotherapy for localized prostate cancer
title Daily online contouring and re-planning versus translation-only correction in neurovascular-sparing magnetic resonance-guided radiotherapy for localized prostate cancer
title_full Daily online contouring and re-planning versus translation-only correction in neurovascular-sparing magnetic resonance-guided radiotherapy for localized prostate cancer
title_fullStr Daily online contouring and re-planning versus translation-only correction in neurovascular-sparing magnetic resonance-guided radiotherapy for localized prostate cancer
title_full_unstemmed Daily online contouring and re-planning versus translation-only correction in neurovascular-sparing magnetic resonance-guided radiotherapy for localized prostate cancer
title_short Daily online contouring and re-planning versus translation-only correction in neurovascular-sparing magnetic resonance-guided radiotherapy for localized prostate cancer
title_sort daily online contouring and re-planning versus translation-only correction in neurovascular-sparing magnetic resonance-guided radiotherapy for localized prostate cancer
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485897/
https://www.ncbi.nlm.nih.gov/pubmed/36148156
http://dx.doi.org/10.1016/j.phro.2022.09.002
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