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Poor Nutritional Status Is Associated with Arrhythmic Events on 24-Hour Holter Recording

BACKGROUND: Malnutrition is associated with cardiovascular disease morbidity and mortality. Arrhythmias may be the cardiac consequences of malnutrition. OBJECTIVES: The objective of the study was to evaluate the association between prognostic nutritional index (PNI), Controlling Nutritional Status (...

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Autores principales: Kurmus Ferik, Ozge, Akbuga, Kursat, Tolunay, Hatice, Aslan, Turgay, Eren, Murat, Erkan, Aycan Fahri, Ekici, Berkay, Akgul Ercan, Ebru, Kervancıoglu, Celal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485921/
https://www.ncbi.nlm.nih.gov/pubmed/35398841
http://dx.doi.org/10.1159/000524396
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author Kurmus Ferik, Ozge
Akbuga, Kursat
Tolunay, Hatice
Aslan, Turgay
Eren, Murat
Erkan, Aycan Fahri
Ekici, Berkay
Akgul Ercan, Ebru
Kervancıoglu, Celal
author_facet Kurmus Ferik, Ozge
Akbuga, Kursat
Tolunay, Hatice
Aslan, Turgay
Eren, Murat
Erkan, Aycan Fahri
Ekici, Berkay
Akgul Ercan, Ebru
Kervancıoglu, Celal
author_sort Kurmus Ferik, Ozge
collection PubMed
description BACKGROUND: Malnutrition is associated with cardiovascular disease morbidity and mortality. Arrhythmias may be the cardiac consequences of malnutrition. OBJECTIVES: The objective of the study was to evaluate the association between prognostic nutritional index (PNI), Controlling Nutritional Status (CONUT) score, and arrhythmic events on 24-h electrocardiography (ECG) Holter recording in patients without manifested arrhythmia. METHODS: In this retrospective analysis of 477 patients who underwent 24-h ECG Holter monitoring, PNI and CONUT score were calculated and patients were divided into tertiles according to PNI and into three groups according to CONUT score; 0: normal, 1–2: mild risk of malnutrition, ≥3: moderate-severe risk of malnutrition. Arrhythmic events were compared between PNI tertiles and CONUT score groups. RESULTS: Total number of premature atrial contractions, premature ventricular contractions (PVCs), PVC burden, and incidence of paroxysmal atrial fibrillation (PAF) were significantly higher in patients within the lowest PNI tertile. Total number of PVCs, PVC burden, and incidence of PAF were significantly higher in patients with CONUT score ≥3. The cut-off value for PNI to predict the presence of PVC was defined as 39.41 using ROC curve analysis. The area under the curve was 0.650 (p < 0.001). Multivariate analysis showed that PNI was independent predictor of the presence of PVC and PAF. Also, CONUT score was independent predictor of the presence of PVC and PAF. Incidence of nonsustained ventricular tachycardia did not differ between PNI tertiles or CONUT score groups. CONCLUSION: Poor nutritional status, assessed by PNI and CONUT score, is associated with arrhythmic events on 24-h ECG Holter recording in patients without manifested arrhythmia.
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spelling pubmed-94859212022-09-23 Poor Nutritional Status Is Associated with Arrhythmic Events on 24-Hour Holter Recording Kurmus Ferik, Ozge Akbuga, Kursat Tolunay, Hatice Aslan, Turgay Eren, Murat Erkan, Aycan Fahri Ekici, Berkay Akgul Ercan, Ebru Kervancıoglu, Celal Med Princ Pract Original Paper BACKGROUND: Malnutrition is associated with cardiovascular disease morbidity and mortality. Arrhythmias may be the cardiac consequences of malnutrition. OBJECTIVES: The objective of the study was to evaluate the association between prognostic nutritional index (PNI), Controlling Nutritional Status (CONUT) score, and arrhythmic events on 24-h electrocardiography (ECG) Holter recording in patients without manifested arrhythmia. METHODS: In this retrospective analysis of 477 patients who underwent 24-h ECG Holter monitoring, PNI and CONUT score were calculated and patients were divided into tertiles according to PNI and into three groups according to CONUT score; 0: normal, 1–2: mild risk of malnutrition, ≥3: moderate-severe risk of malnutrition. Arrhythmic events were compared between PNI tertiles and CONUT score groups. RESULTS: Total number of premature atrial contractions, premature ventricular contractions (PVCs), PVC burden, and incidence of paroxysmal atrial fibrillation (PAF) were significantly higher in patients within the lowest PNI tertile. Total number of PVCs, PVC burden, and incidence of PAF were significantly higher in patients with CONUT score ≥3. The cut-off value for PNI to predict the presence of PVC was defined as 39.41 using ROC curve analysis. The area under the curve was 0.650 (p < 0.001). Multivariate analysis showed that PNI was independent predictor of the presence of PVC and PAF. Also, CONUT score was independent predictor of the presence of PVC and PAF. Incidence of nonsustained ventricular tachycardia did not differ between PNI tertiles or CONUT score groups. CONCLUSION: Poor nutritional status, assessed by PNI and CONUT score, is associated with arrhythmic events on 24-h ECG Holter recording in patients without manifested arrhythmia. S. Karger AG 2022-04-08 /pmc/articles/PMC9485921/ /pubmed/35398841 http://dx.doi.org/10.1159/000524396 Text en Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC). Usage and distribution for commercial purposes requires written permission. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
spellingShingle Original Paper
Kurmus Ferik, Ozge
Akbuga, Kursat
Tolunay, Hatice
Aslan, Turgay
Eren, Murat
Erkan, Aycan Fahri
Ekici, Berkay
Akgul Ercan, Ebru
Kervancıoglu, Celal
Poor Nutritional Status Is Associated with Arrhythmic Events on 24-Hour Holter Recording
title Poor Nutritional Status Is Associated with Arrhythmic Events on 24-Hour Holter Recording
title_full Poor Nutritional Status Is Associated with Arrhythmic Events on 24-Hour Holter Recording
title_fullStr Poor Nutritional Status Is Associated with Arrhythmic Events on 24-Hour Holter Recording
title_full_unstemmed Poor Nutritional Status Is Associated with Arrhythmic Events on 24-Hour Holter Recording
title_short Poor Nutritional Status Is Associated with Arrhythmic Events on 24-Hour Holter Recording
title_sort poor nutritional status is associated with arrhythmic events on 24-hour holter recording
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485921/
https://www.ncbi.nlm.nih.gov/pubmed/35398841
http://dx.doi.org/10.1159/000524396
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