Unexpected Small-Bowel Finding in Overt-Obscure Gastrointestinal Bleeding in a Patient with Neurofibromatosis Type 1 and Crohn's Disease

Gastrointestinal stromal tumors (GIST) are the most frequent mesenchymal neoplasms affecting the gastrointestinal tract, and the small bowel is the second most frequent location. Approximately 5% of patients with GIST are not sporadic and have a familial autosomal dominant syndrome, such as neurofib...

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Autores principales: Gomes, Catarina, Ponte, Ana, Pinho, Rolando, Rodrigues, Adélia, Carvalho, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Clinical Case Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485953/
https://www.ncbi.nlm.nih.gov/pubmed/36159194
http://dx.doi.org/10.1159/000518326
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author Gomes, Catarina
Ponte, Ana
Pinho, Rolando
Rodrigues, Adélia
Carvalho, João
author_facet Gomes, Catarina
Ponte, Ana
Pinho, Rolando
Rodrigues, Adélia
Carvalho, João
author_sort Gomes, Catarina
collection PubMed
description Gastrointestinal stromal tumors (GIST) are the most frequent mesenchymal neoplasms affecting the gastrointestinal tract, and the small bowel is the second most frequent location. Approximately 5% of patients with GIST are not sporadic and have a familial autosomal dominant syndrome, such as neurofibromatosis type 1 (NF1). Gastrointestinal bleeding is a common presentation of GIST, and lesions such as submucosal tumors may be detected more readily by capsule endoscopy due to luminal impingement and overlying ulceration. Our report emphasizes the importance of small-bowel investigation in patients with Crohn's disease and NF1 presenting with recent overt bleeding.
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spelling pubmed-94859532022-09-23 Unexpected Small-Bowel Finding in Overt-Obscure Gastrointestinal Bleeding in a Patient with Neurofibromatosis Type 1 and Crohn's Disease Gomes, Catarina Ponte, Ana Pinho, Rolando Rodrigues, Adélia Carvalho, João GE Port J Gastroenterol Clinical Case Study Gastrointestinal stromal tumors (GIST) are the most frequent mesenchymal neoplasms affecting the gastrointestinal tract, and the small bowel is the second most frequent location. Approximately 5% of patients with GIST are not sporadic and have a familial autosomal dominant syndrome, such as neurofibromatosis type 1 (NF1). Gastrointestinal bleeding is a common presentation of GIST, and lesions such as submucosal tumors may be detected more readily by capsule endoscopy due to luminal impingement and overlying ulceration. Our report emphasizes the importance of small-bowel investigation in patients with Crohn's disease and NF1 presenting with recent overt bleeding. S. Karger AG 2021-08-18 /pmc/articles/PMC9485953/ /pubmed/36159194 http://dx.doi.org/10.1159/000518326 Text en Copyright © 2021 by Sociedade Portuguesa de Gastrenterologia Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC). Usage and distribution for commercial purposes requires written permission. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
spellingShingle Clinical Case Study
Gomes, Catarina
Ponte, Ana
Pinho, Rolando
Rodrigues, Adélia
Carvalho, João
Unexpected Small-Bowel Finding in Overt-Obscure Gastrointestinal Bleeding in a Patient with Neurofibromatosis Type 1 and Crohn's Disease
title Unexpected Small-Bowel Finding in Overt-Obscure Gastrointestinal Bleeding in a Patient with Neurofibromatosis Type 1 and Crohn's Disease
title_full Unexpected Small-Bowel Finding in Overt-Obscure Gastrointestinal Bleeding in a Patient with Neurofibromatosis Type 1 and Crohn's Disease
title_fullStr Unexpected Small-Bowel Finding in Overt-Obscure Gastrointestinal Bleeding in a Patient with Neurofibromatosis Type 1 and Crohn's Disease
title_full_unstemmed Unexpected Small-Bowel Finding in Overt-Obscure Gastrointestinal Bleeding in a Patient with Neurofibromatosis Type 1 and Crohn's Disease
title_short Unexpected Small-Bowel Finding in Overt-Obscure Gastrointestinal Bleeding in a Patient with Neurofibromatosis Type 1 and Crohn's Disease
title_sort unexpected small-bowel finding in overt-obscure gastrointestinal bleeding in a patient with neurofibromatosis type 1 and crohn's disease
topic Clinical Case Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485953/
https://www.ncbi.nlm.nih.gov/pubmed/36159194
http://dx.doi.org/10.1159/000518326
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