Cargando…
Differential Internalization of Thrombin-Derived Host Defense Peptides into Monocytes and Macrophages
Proteolytic cleavage of thrombin generates C-terminal host defense peptides exerting multiple immunomodulatory effects in response to bacterial stimuli. Previously, we reported that thrombin-derived C-terminal peptides (TCPs) are internalized in monocytes and macrophages in a time- and temperature-d...
Autores principales: | Hansen, Finja C., Nadeem, Aftab, Browning, Kathryn L., Campana, Mario, Schmidtchen, Artur, van der Plas, Mariena J.A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485985/ https://www.ncbi.nlm.nih.gov/pubmed/34937021 http://dx.doi.org/10.1159/000520831 |
Ejemplares similares
-
Thrombin-Derived Host-Defense Peptides Modulate Monocyte/Macrophage Inflammatory Responses to Gram-Negative Bacteria
por: Hansen, Finja C., et al.
Publicado: (2017) -
Host Defense Peptides of Thrombin Modulate Inflammation and Coagulation in Endotoxin-Mediated Shock and Pseudomonas aeruginosa Sepsis
por: Kalle, Martina, et al.
Publicado: (2012) -
Proteolysis of Human Thrombin Generates Novel Host Defense Peptides
por: Papareddy, Praveen, et al.
Publicado: (2010) -
Pseudomonas aeruginosa elastase cleaves a C-terminal peptide from human thrombin that inhibits host inflammatory responses
por: van der Plas, Mariena J. A., et al.
Publicado: (2016) -
Proteolytic signatures define unique thrombin-derived peptides present in human wound fluid in vivo
por: Saravanan, Rathi, et al.
Publicado: (2017)