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Detection of stage I HPV-driven oropharyngeal cancer in asymptomatic individuals in the Hamburg City Health Study using HPV16 E6 serology – A proof-of-concept study
BACKGROUND: The lack of detectable precancerous lesions poses challenges to the early detection of human papillomavirus-driven oropharyngeal cancer (HPV-OPC). Antibodies against HPV16 early proteins, especially E6, are uniquely sensitive and specific biomarkers detectable years prior to HPV-OPC diag...
Autores principales: | Busch, Chia-Jung, Hoffmann, Anna Sophie, Viarisio, Daniele, Becker, Benjamin T., Rieckmann, Thorsten, Betz, Christian, Bender, Noemi, Schroeder, Lea, Hussein, Yassin, Petersen, Elina, Jagodzinski, Annika, Schäfer, Ines, Burandt, Eike, Lang Kuhs, Krystle, Pawlita, Michael, Waterboer, Tim, Brenner, Nicole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486032/ https://www.ncbi.nlm.nih.gov/pubmed/36147627 http://dx.doi.org/10.1016/j.eclinm.2022.101659 |
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