Balancing cell polarity PARts through dephosphorylation

How cells spatially organize their plasma membrane, cytoskeleton, and cytoplasm remains a central question for cell biologists. In this issue of JCB, Calvi et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202201048) identify PP1 phosphatases as key regulators of C. elegans anterior–posterior...

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Detalles Bibliográficos
Autores principales: Barros-Carvalho, André, Morais-de-Sá, Eurico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486083/
https://www.ncbi.nlm.nih.gov/pubmed/36121422
http://dx.doi.org/10.1083/jcb.202208008
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author Barros-Carvalho, André
Morais-de-Sá, Eurico
author_facet Barros-Carvalho, André
Morais-de-Sá, Eurico
author_sort Barros-Carvalho, André
collection PubMed
description How cells spatially organize their plasma membrane, cytoskeleton, and cytoplasm remains a central question for cell biologists. In this issue of JCB, Calvi et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202201048) identify PP1 phosphatases as key regulators of C. elegans anterior–posterior polarity, by counterbalancing aPKC-mediated phosphorylation of PAR-2.
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spelling pubmed-94860832023-03-19 Balancing cell polarity PARts through dephosphorylation Barros-Carvalho, André Morais-de-Sá, Eurico J Cell Biol Spotlight How cells spatially organize their plasma membrane, cytoskeleton, and cytoplasm remains a central question for cell biologists. In this issue of JCB, Calvi et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202201048) identify PP1 phosphatases as key regulators of C. elegans anterior–posterior polarity, by counterbalancing aPKC-mediated phosphorylation of PAR-2. Rockefeller University Press 2022-09-19 /pmc/articles/PMC9486083/ /pubmed/36121422 http://dx.doi.org/10.1083/jcb.202208008 Text en © 2022 Barros-Carvalho and Morais-de-Sa https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
Barros-Carvalho, André
Morais-de-Sá, Eurico
Balancing cell polarity PARts through dephosphorylation
title Balancing cell polarity PARts through dephosphorylation
title_full Balancing cell polarity PARts through dephosphorylation
title_fullStr Balancing cell polarity PARts through dephosphorylation
title_full_unstemmed Balancing cell polarity PARts through dephosphorylation
title_short Balancing cell polarity PARts through dephosphorylation
title_sort balancing cell polarity parts through dephosphorylation
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486083/
https://www.ncbi.nlm.nih.gov/pubmed/36121422
http://dx.doi.org/10.1083/jcb.202208008
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