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Proteasomal degradation of WT proinsulin in pancreatic beta cells

Preproinsulin entry into the endoplasmic reticulum yields proinsulin, and its subsequent delivery to the distal secretory pathway leads to processing, storage, and secretion of mature insulin. Multiple groups have reported that treatment of pancreatic beta cell lines, rodent pancreatic islets, or hu...

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Detalles Bibliográficos
Autores principales:	Xu, Xiaoxi, Arunagiri, Anoop, Haataja, Leena, Alam, Maroof, Ji, Shuhui, Qi, Ling, Tsai, Billy, Liu, Ming, Arvan, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486123/ https://www.ncbi.nlm.nih.gov/pubmed/35988641 http://dx.doi.org/10.1016/j.jbc.2022.102406

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