Cargando…

Complex And Simple Appendicitis: REstrictive or Liberal postoperative Antibiotic eXposure (CASA RELAX) using Desirability of Outcome Ranking (DOOR) and Response Adjusted for Duration of Antibiotic Risk (RADAR): study protocol for a randomized controlled trial

OBJECTIVES: After appendectomy for simple or complicated appendicitis, the optimal duration of postoperative antibiotics (postop abx) is unclear and great practice variability exists. We propose to compare restrictive versus liberal postop abx using a hierarchical composite endpoint which includes p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yeh, Daniel Dante, Hatton, Gabrielle E, Pedroza, Claudia, Pust, Gerd, Mantero, Alejandro, Namias, Nicholas, Kao, Lillian S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486380/ https://www.ncbi.nlm.nih.gov/pubmed/36148315 http://dx.doi.org/10.1136/tsaco-2022-000931

Ejemplares similares

1005. The Antibiotic Optimization DOOR: Refining Assessment of Antibiotic Therapy with Desirability of Outcome Ranking
por: Smoke, Steven, et al.
Publicado: (2019)

2581. Desirability of Outcome Ranking and Response Adjusted for Antibiotic Risk (DOOR/RADAR) Post-Hoc Analysis Supports Equipoise for Antibiotic Initiation Strategies in ICU-Acquired Pneumonia
por: Guidry, Christopher A, et al.
Publicado: (2023)

Reply: From the “Door-to-Antibiotic” to the “Antibiotic-at-Door” Concept?
por: Peltan, Ithan D., et al.
Publicado: (2019)

Comparing the Clinical Utility of Rapid Diagnostics for Treatment of Bloodstream Infections Using Desirability of Outcome Ranking Approach for the Management of Antibiotic Therapy (DOOR-MAT)
por: Claeys, Kimberly C., et al.
Publicado: (2021)

2905. Development of a Desirability of Outcome Ranking (DOOR) for Skin Infection Clinical Trials
por: Miller, Loren G, et al.
Publicado: (2023)

369. The DOOR is open: A Web-based Application for Analyzing the Desirability of Outcome Ranking
por: Hamasaki, Toshimitsu, et al.
Publicado: (2023)

Prehospital Emergency Care in Sepsis: From the “Door-to-Antibiotic” to the “Antibiotic-at-Door” Concept?
por: Jouffroy, Romain, et al.
Publicado: (2019)

1757. Using the Desirability of Outcome Ranking for Management of Antimicrobial Therapy (DOOR-MAT) to Assess Antibiotic Therapy Guided by Rapid Molecular Diagnostics (RMD) in Bloodstream Infection (BSI) Caused by Escherichia coli and Klebsiella pneumoniae
por: Wilson, Brigid, et al.
Publicado: (2018)

2168. Comparison of Rapid Diagnostic Tests for Bloodstream Infections Using Desirability of Outcome Ranking Management of Antimicrobial Therapy (DOOR-MAT)
por: Claeys, Kimberly C, et al.
Publicado: (2019)

Antibiotics alone in the treatment of appendicitis
por: Farooq, Ameer, et al.
Publicado: (2021)

1978. Statements about Antibiotic Side-Effects and Patient Desire for Unnecessary Antibiotics
por: Miller, Benjamin, et al.
Publicado: (2019)

Risk classification and door-to-antibiotic time in patients with suspected sepsis
por: Lima, Ana Paula Souza, et al.
Publicado: (2023)

Ranking, selecting, and prioritising genes with desirability functions
por: Lazic, Stanley E.
Publicado: (2015)

Applying Desirability of Outcome Ranking End Points
por: Dunne, Michael W, et al.
Publicado: (2023)

Uses of Antibiotics Alone in Case of Uncomplicated Appendicitis
por: Yadao, Siddhartha, et al.
Publicado: (2022)

Management of appendicitis: appendicectomy, antibiotic therapy, or both?
por: Weledji, Elroy P., et al.
Publicado: (2023)

2106. Desirability of Outcome Ranking (DOOR): Application to a Phase 3 Registrational Trial Evaluating Sulopenem for Patients with Complicated Intra-abdominal Infection (cIAI)
por: Aronin, Steven I, et al.
Publicado: (2023)

Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens
por: Ng, Katharine M., et al.
Publicado: (2013)

Oral metronidazole as antibiotic prophylaxis for patients with nonperforated appendicitis
por: Ravari, Hassan, et al.
Publicado: (2011)

Combating homophobia, lesbophobia, biphobia and transphobia: A liberating and subversive educational alternative for desires
por: Barragán-Medero, Fernando, et al.
Publicado: (2020)

A Desirability of Outcome Ranking Analysis of a Randomized Clinical Trial Comparing Seven Versus Fourteen Days of Antibiotics for Uncomplicated Gram-Negative Bloodstream Infection
por: Howard-Anderson, Jessica, et al.
Publicado: (2022)

Antibiotics versus appendicectomy in the management of acute appendicitis: an ongoing debate
por: Fitzmaurice, Gerard J., et al.
Publicado: (2012)

Early Antibiotics in Septic Shock: A Desirable Goal but “Curb Your Enthusiasm”
por: Hegde, Ashit
Publicado: (2023)

Synergy by Perturbing the Gram-Negative Outer Membrane: Opening the Door for Gram-Positive Specific Antibiotics
por: Wesseling, Charlotte M. J., et al.
Publicado: (2022)

Bacteriology and Changes in Antibiotic Susceptibility in Adults with Community-Acquired Perforated Appendicitis
por: Jeon, Hong Gil, et al.
Publicado: (2014)

Meta‐analysis of antibiotics versus appendicectomy for non‐perforated acute appendicitis
por: Sallinen, V., et al.
Publicado: (2016)

Postoperative antibiotic therapy after appendectomy in patients with non-perforated appendicitis
por: Sadraei-Moosavi, Seyed-Mohammadreza, et al.
Publicado: (2017)

Long-Term Results Following Antibiotic Treatment of Acute Appendicitis in Adults
por: Lundholm, K., et al.
Publicado: (2017)

The role of postoperative antibiotics in preventing surgical site infections in uncomplicated appendicitis
por: Abounozha, Sabry, et al.
Publicado: (2021)

Appropriate Antibiotic Selection during the in-hospital Waiting Period for Surgery for Appendicitis
por: Yukumi, Shungo, et al.
Publicado: (2022)

1886. Provider’s Close Approximation of Parental Desire for Antibiotics Does Not Diminish Concern of Anticipated Conflict
por: Myers, Angela, et al.
Publicado: (2018)

Prolonged Antibiotic Treatment does not Prevent Intra-Abdominal Abscesses in Perforated Appendicitis
por: van Wijck, K., et al.
Publicado: (2010)

Meta-analysis of the therapeutic effects of antibiotic versus appendicectomy for the treatment of acute appendicitis
por: LIU, ZHI-HUA, et al.
Publicado: (2014)

Methods of conservative antibiotic treatment of acute uncomplicated appendicitis: A systematic review
por: Talan, David A., et al.
Publicado: (2019)

2412 Cost effectiveness analysis of operative Versus antibiotic management for uncomplicated appendicitis
por: Stulberg, Eric, et al.
Publicado: (2018)

Laparoscopic appendectomy versus antibiotic treatment for acute appendicitis—a systematic review
por: Köhler, Franziska, et al.
Publicado: (2021)

Cost-Utility Analysis of Antibiotic Therapy versus Appendicectomy for Acute Uncomplicated Appendicitis
por: Ali, Ayesha, et al.
Publicado: (2021)

Antibiotic treatment for appendicitis in Norway and Sweden: a nationwide survey on treatment practices
por: Gran, M. V., et al.
Publicado: (2022)

Postoperative Antibiotics and Time to Reach Discharge Criteria after Appendectomy for Complex Appendicitis
por: van den Boom, Anne Loes, et al.
Publicado: (2023)

Bacterial profile and antibiotic selection for pediatric appendicitis: A retrospective cohort study
por: Naji, Hussein, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_40gbvt7936b0u6oj3trebknepc