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HSP90α induces immunosuppressive myeloid cells in melanoma via TLR4 signaling

BACKGROUND: Tumor cells modulate host immunity by secreting extracellular vesicles (EV) and soluble factors. Their interactions with myeloid cells lead to the generation of myeloid-derived suppressor cells (MDSC), which inhibit the antitumor function of T and NK cells. We demonstrated previously tha...

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Detalles Bibliográficos
Autores principales:	Arkhypov, Ihor, Özbay Kurt, Feyza Gül, Bitsch, Rebekka, Novak, Daniel, Petrova, Vera, Lasser, Samantha, Hielscher, Thomas, Groth, Christopher, Lepper, Alisa, Hu, Xiaoying, Li, Wei, Utikal, Jochen, Altevogt, Peter, Umansky, Viktor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486388/ https://www.ncbi.nlm.nih.gov/pubmed/36113897 http://dx.doi.org/10.1136/jitc-2022-005551

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