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Integrated transcriptomics and metabolomics analysis of the hippocampus reveals altered neuroinflammation, downregulated metabolism and synapse in sepsis-associated encephalopathy
Sepsis-associated encephalopathy (SAE) is an intricated complication of sepsis that brings abnormal emotional and memory dysfunction and increases patients’ mortality. Patients’ alterations and abnormal function seen in SAE occur in the hippocampus, the primary brain region responsible for memory an...
Autores principales: | Xu, Kejia, Li, Hui, Zhang, Bing, Le, Meini, Huang, Qiong, Fu, Rao, Croppi, Giorgia, Qian, Gang, Zhang, Junjie, Zhang, Guangming, Lu, Yinzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486403/ https://www.ncbi.nlm.nih.gov/pubmed/36147346 http://dx.doi.org/10.3389/fphar.2022.1004745 |
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