Integrated transcriptomics and metabolomics analysis of the hippocampus reveals altered neuroinflammation, downregulated metabolism and synapse in sepsis-associated encephalopathy

Sepsis-associated encephalopathy (SAE) is an intricated complication of sepsis that brings abnormal emotional and memory dysfunction and increases patients’ mortality. Patients’ alterations and abnormal function seen in SAE occur in the hippocampus, the primary brain region responsible for memory an...

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Detalles Bibliográficos
Autores principales: Xu, Kejia, Li, Hui, Zhang, Bing, Le, Meini, Huang, Qiong, Fu, Rao, Croppi, Giorgia, Qian, Gang, Zhang, Junjie, Zhang, Guangming, Lu, Yinzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486403/
https://www.ncbi.nlm.nih.gov/pubmed/36147346
http://dx.doi.org/10.3389/fphar.2022.1004745

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