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Langerhans Cell Histiocytosis of the Mandible
The unusual disorder known as Langerhans cell histiocytosis, which is most frequently seen in children and young adults, is caused by the clonal proliferation of Langerhans cells. Even if clinical signs and radiographic evidence of destructive bone lesions may raise suspicion of the disease, a relia...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486456/ https://www.ncbi.nlm.nih.gov/pubmed/36158441 http://dx.doi.org/10.7759/cureus.28222 |
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author | Padmanaban, Kamalakannan Kamalakaran, Arunkumar Raghavan, Priyadharshini Palani, Triveni Rajiah, Davidson |
author_facet | Padmanaban, Kamalakannan Kamalakaran, Arunkumar Raghavan, Priyadharshini Palani, Triveni Rajiah, Davidson |
author_sort | Padmanaban, Kamalakannan |
collection | PubMed |
description | The unusual disorder known as Langerhans cell histiocytosis, which is most frequently seen in children and young adults, is caused by the clonal proliferation of Langerhans cells. Even if clinical signs and radiographic evidence of destructive bone lesions may raise suspicion of the disease, a reliable diagnosis without a thorough pathological examination is challenging. This report describes a case of eosinophilic granuloma of the mandible in a nine-year-old child with characteristic radiological, histopathological, and immunohistochemical features. |
format | Online Article Text |
id | pubmed-9486456 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-94864562022-09-23 Langerhans Cell Histiocytosis of the Mandible Padmanaban, Kamalakannan Kamalakaran, Arunkumar Raghavan, Priyadharshini Palani, Triveni Rajiah, Davidson Cureus Pathology The unusual disorder known as Langerhans cell histiocytosis, which is most frequently seen in children and young adults, is caused by the clonal proliferation of Langerhans cells. Even if clinical signs and radiographic evidence of destructive bone lesions may raise suspicion of the disease, a reliable diagnosis without a thorough pathological examination is challenging. This report describes a case of eosinophilic granuloma of the mandible in a nine-year-old child with characteristic radiological, histopathological, and immunohistochemical features. Cureus 2022-08-21 /pmc/articles/PMC9486456/ /pubmed/36158441 http://dx.doi.org/10.7759/cureus.28222 Text en Copyright © 2022, Padmanaban et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Pathology Padmanaban, Kamalakannan Kamalakaran, Arunkumar Raghavan, Priyadharshini Palani, Triveni Rajiah, Davidson Langerhans Cell Histiocytosis of the Mandible |
title | Langerhans Cell Histiocytosis of the Mandible |
title_full | Langerhans Cell Histiocytosis of the Mandible |
title_fullStr | Langerhans Cell Histiocytosis of the Mandible |
title_full_unstemmed | Langerhans Cell Histiocytosis of the Mandible |
title_short | Langerhans Cell Histiocytosis of the Mandible |
title_sort | langerhans cell histiocytosis of the mandible |
topic | Pathology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486456/ https://www.ncbi.nlm.nih.gov/pubmed/36158441 http://dx.doi.org/10.7759/cureus.28222 |
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