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Langerhans Cell Histiocytosis of the Mandible

The unusual disorder known as Langerhans cell histiocytosis, which is most frequently seen in children and young adults, is caused by the clonal proliferation of Langerhans cells. Even if clinical signs and radiographic evidence of destructive bone lesions may raise suspicion of the disease, a relia...

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Detalles Bibliográficos
Autores principales: Padmanaban, Kamalakannan, Kamalakaran, Arunkumar, Raghavan, Priyadharshini, Palani, Triveni, Rajiah, Davidson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486456/
https://www.ncbi.nlm.nih.gov/pubmed/36158441
http://dx.doi.org/10.7759/cureus.28222
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author Padmanaban, Kamalakannan
Kamalakaran, Arunkumar
Raghavan, Priyadharshini
Palani, Triveni
Rajiah, Davidson
author_facet Padmanaban, Kamalakannan
Kamalakaran, Arunkumar
Raghavan, Priyadharshini
Palani, Triveni
Rajiah, Davidson
author_sort Padmanaban, Kamalakannan
collection PubMed
description The unusual disorder known as Langerhans cell histiocytosis, which is most frequently seen in children and young adults, is caused by the clonal proliferation of Langerhans cells. Even if clinical signs and radiographic evidence of destructive bone lesions may raise suspicion of the disease, a reliable diagnosis without a thorough pathological examination is challenging. This report describes a case of eosinophilic granuloma of the mandible in a nine-year-old child with characteristic radiological, histopathological, and immunohistochemical features.
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spelling pubmed-94864562022-09-23 Langerhans Cell Histiocytosis of the Mandible Padmanaban, Kamalakannan Kamalakaran, Arunkumar Raghavan, Priyadharshini Palani, Triveni Rajiah, Davidson Cureus Pathology The unusual disorder known as Langerhans cell histiocytosis, which is most frequently seen in children and young adults, is caused by the clonal proliferation of Langerhans cells. Even if clinical signs and radiographic evidence of destructive bone lesions may raise suspicion of the disease, a reliable diagnosis without a thorough pathological examination is challenging. This report describes a case of eosinophilic granuloma of the mandible in a nine-year-old child with characteristic radiological, histopathological, and immunohistochemical features. Cureus 2022-08-21 /pmc/articles/PMC9486456/ /pubmed/36158441 http://dx.doi.org/10.7759/cureus.28222 Text en Copyright © 2022, Padmanaban et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Padmanaban, Kamalakannan
Kamalakaran, Arunkumar
Raghavan, Priyadharshini
Palani, Triveni
Rajiah, Davidson
Langerhans Cell Histiocytosis of the Mandible
title Langerhans Cell Histiocytosis of the Mandible
title_full Langerhans Cell Histiocytosis of the Mandible
title_fullStr Langerhans Cell Histiocytosis of the Mandible
title_full_unstemmed Langerhans Cell Histiocytosis of the Mandible
title_short Langerhans Cell Histiocytosis of the Mandible
title_sort langerhans cell histiocytosis of the mandible
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486456/
https://www.ncbi.nlm.nih.gov/pubmed/36158441
http://dx.doi.org/10.7759/cureus.28222
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AT palanitriveni langerhanscellhistiocytosisofthemandible
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