Oral N-acetylcysteine decreases IFN-γ production and ameliorates ischemia-reperfusion injury in steatotic livers

Type 1 Natural Killer T-cells (NKT1 cells) play a critical role in mediating hepatic ischemia-reperfusion injury (IRI). Although hepatic steatosis is a major risk factor for preservation type injury, how NKT cells impact this is understudied. Given NKT1 cell activation by phospholipid ligands recogn...

Descripción completa

Detalles Bibliográficos
Autores principales: Liggett, Jedson R., Kang, Jiman, Ranjit, Suman, Rodriguez, Olga, Loh, Katrina, Patil, Digvijay, Cui, Yuki, Duttargi, Anju, Nguyen, Sang, He, Britney, Lee, Yichien, Oza, Kesha, Frank, Brett S., Kwon, DongHyang, Li, Heng-Hong, Kallakury, Bhaskar, Libby, Andrew, Levi, Moshe, Robson, Simon C., Fishbein, Thomas M., Cui, Wanxing, Albanese, Chris, Khan, Khalid, Kroemer, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486542/
https://www.ncbi.nlm.nih.gov/pubmed/36148239
http://dx.doi.org/10.3389/fimmu.2022.898799

Ejemplares similares

Ejemplares similares