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Inflammatory activation of the FcγR and IFNγR pathways co-influences the differentiation and activity of osteoclasts
Osteoclasts are polykaryons formed by cell–cell fusion of highly motile progenitors of the myeloid lineage. Osteoclast activity can preserve skeletal strength and bone homeostasis. However, osteoclasts are responsible for bone destruction in rheumatoid arthritis (RA). Fc receptors activated by IgG i...
Autores principales: | Groetsch, Bettina, Schachtschabel, Elisabeth, Tripal, Philipp, Schmid, Benjamin, Smith, Ana-Suncana, Schett, Georg, Bozec, Aline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486546/ https://www.ncbi.nlm.nih.gov/pubmed/36148242 http://dx.doi.org/10.3389/fimmu.2022.958974 |
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