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Inflammatory activation of the FcγR and IFNγR pathways co-influences the differentiation and activity of osteoclasts

Osteoclasts are polykaryons formed by cell–cell fusion of highly motile progenitors of the myeloid lineage. Osteoclast activity can preserve skeletal strength and bone homeostasis. However, osteoclasts are responsible for bone destruction in rheumatoid arthritis (RA). Fc receptors activated by IgG i...

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Detalles Bibliográficos
Autores principales: Groetsch, Bettina, Schachtschabel, Elisabeth, Tripal, Philipp, Schmid, Benjamin, Smith, Ana-Suncana, Schett, Georg, Bozec, Aline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486546/
https://www.ncbi.nlm.nih.gov/pubmed/36148242
http://dx.doi.org/10.3389/fimmu.2022.958974

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